Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1034 6
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
LEP P41159 leptin 0.46 0.349 0.846 931 15
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 749 15
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 737 18
MIR21 microRNA 21 0.363 0.846 726 2
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45