Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 23
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692 19
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 18
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808 17
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
PTAFR P25105 platelet activating factor receptor G-protein coupled receptor 0.24 0.575 0.731 17
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 17
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 16
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731 16
NFKBIA P25963 NFKB inhibitor alpha 0.99 0.487 0.885 16
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 16
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 15
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 15
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 15
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 13
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 12
HRH3 Q9Y5N1 histamine receptor H3 G-protein coupled receptor 4.1E-02 0.647 0.462 12
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 12
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885 12
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731 10
CASP7 P55210 caspase 7 Enzyme 5.4E-05 0.581 0.654 9
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 9