Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808 40
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 39
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808 38
CD40 P25942 CD40 molecule 0.85 0.396 0.846 36
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846 36
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 35
ITGB1 P05556 integrin subunit beta 1 Receptor 0.98 0.496 0.808 34
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 33
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 29
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 28
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731 28
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 27
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769 23
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 23
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 21
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731 20
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808 19
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923 19
CXCL13 O43927 C-X-C motif chemokine ligand 13 Signaling 0.83 0.472 0.731 18
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808 18
SDC1 P18827 syndecan 1 Extracellular structure 8.4E-03 0.445 0.769 18
CCL21 O00585 C-C motif chemokine ligand 21 Signaling 3.6E-02 0.502 0.769 17
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 17