Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 54 17
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731 49 4
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49 1
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 48 34
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885 48 0
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 47 99
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 44 5
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654 43 320
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885 42 5
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769 41 3
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808 39 3
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 39 1
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 37 28
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 37 8
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692 35 50
KRT8 P05787 keratin 8 2.4E-08 0.517 0.654 35 7
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885 33 6
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 32 29
FLCN Q8NFG4 folliculin 0.79 0.537 0.885 30 122
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885 30 1
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731 28 85
CCNH P51946 cyclin H Enzyme modulator 8.1E-04 0.595 0.769 28 30