Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 232 407
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 164 35
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 120 21
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 115 105
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 115 90
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 113 95
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 110 65
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 108 72
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 94 70
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 91 10
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 89 14
IL2 P60568 interleukin 2 0.48 0.336 0.885 75 3
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 73 6
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 72 75
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 67 6