Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 826 38
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 762 4
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 722 20
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 665 33
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 647 13
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 611 20
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 594 5
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 584 17
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 577 7
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 561 21
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 546 5
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923 538 2
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923 537 8
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923 529 6
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923 528 3
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923 526 3
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 525 37
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 525 4
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923 523 2
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 510 21
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 501 29