Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 64
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 63
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 60
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 54
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 53
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 53
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 53
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 52
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
CDH1 P12830 cadherin 1 0.15 0.401 0.808 50
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 50
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 50
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808 50
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 49
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 49
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 49
SELE P16581 selectin E 7.9E-10 0.447 0.808 49
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 47
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 47
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 46
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 46
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 45