Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IFNB1 P01574 interferon beta 1 0.421 0.846 49
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731 49
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 41
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769 39
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 38
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 38
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 38
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 37
PAX6 P26367 paired box 6 1.00 0.450 0.769 37
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462 36
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846 34
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808 33
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 30
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 30
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 27
PRAME P78395 preferentially expressed antigen in melanoma 2.4E-07 0.531 0.577 27
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769 27
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846 26
SLC5A5 Q92911 solute carrier family 5 member 5 Transporter 2.9E-03 0.499 0.769 26
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885 25
IFNA1 P01562 interferon alpha 1 0.371 0.923 24
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731 24
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846 23
SUZ12 Q15022 SUZ12 polycomb repressive complex 2 subunit Nucleic acid binding 1.00 0.529 0.577 23