Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 87 79
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 85 5
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 78 18
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 77 0
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 75 6
IL2 P60568 interleukin 2 0.48 0.336 0.885 75 3
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 72 75
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 68 36
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 67 0
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 62 2
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 60 11
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 60 1
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 58 9
SST P61278 somatostatin Signaling 0.34 0.399 0.885 56 0
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 53 5
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 51 62
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 51 5
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846 50 34
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 49 33