Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808 2 26
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 9 44
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885 3 1
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 5 1
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 3 2