Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 91 10
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62 3
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 60 11
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 57 2505
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923 55 0
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 53 1
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 52 0
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 48 2
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 45 8
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923 43 30
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 32 0
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 30 33
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 26 4
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923 23 4
VCP P55072 valosin containing protein 1.00 0.469 0.923 19 17
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 8 9
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93