Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 34
CLU P10909 clusterin 7.8E-05 0.426 0.885 14
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885 14
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 24
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 14
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769 17
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 2
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 14
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846 11
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731 5
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 15
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 13
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 17
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808 6
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808 5
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13
HAVCR1 Q96D42 hepatitis A virus cellular receptor 1 8.5E-07 0.489 0.885 10
NR4A1 P22736 nuclear receptor subfamily 4 group A member 1 Nuclear receptor 0.37 0.490 0.731 2
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846 12
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22