Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 40
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885 40
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 39
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 39
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 39
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 37
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 37
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 36
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885 36
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 35
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 35
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808 35
PLAUR Q03405 plasminogen activator, urokinase receptor 5.3E-03 0.536 0.731 35
ITGB1 P05556 integrin subunit beta 1 Receptor 0.98 0.496 0.808 34
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 33
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 33
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 32
IL2 P60568 interleukin 2 0.48 0.336 0.885 32
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 31
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 31
ENG P17813 endoglin 1.00 0.446 0.846 28
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 27
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 27