Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.958 128 0 1987 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1, DNA repair associated 0.410 0.862 1.8E-28
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.937 120 0 1987 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.965 111 0 1988 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.971 66 0 1983 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.940 65 0 1995 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.700 0.956 11 0 2005 2018
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.416 0.828 7.2E-03
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.600 1.000 10 0 1999 2013
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
matrix metallopeptidase 1 0.415 0.793 6.2E-18
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.600 1.000 7 0 1997 2015
Entrez Id: 580
Gene Symbol: BARD1
BARD1
BRCA1 associated RING domain 1 0.624 0.379 2.2E-24
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.550 1.000 4 0 2004 2009
Entrez Id: 4214
Gene Symbol: MAP3K1
MAP3K1
mitogen-activated protein kinase kinase kinase 1 0.569 0.586 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.530 3 0 2007 2009
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
checkpoint kinase 2 0.494 0.621 1.2E-23
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 0.750 40 0 2002 2016
Entrez Id: 472
Gene Symbol: ATM
ATM
ATM serine/threonine kinase 0.401 0.862 6.0E-46
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 0.818 27 0 1996 2015
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 1.000 18 0 2002 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 1.000 14 0 1999 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
partner and localizer of BRCA2 0.569 0.552 7.3E-20
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 1.000 9 0 2006 2017
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
fibroblast growth factor receptor 2 0.398 0.759 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 0.889 8 0 1991 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
erb-b2 receptor tyrosine kinase 3 0.473 0.690 6.7E-15
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 1.000 5 0 1990 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.404 0.828 8.7E-02
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.500 0.875 2 0 1989 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
F-box and WD repeat domain containing 7 0.511 0.759 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.420 < 0.001 1 0 2008 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 0.956 33 0 1990 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 1.000 33 0 2001 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
estrogen receptor 2 0.445 0.828 5.4E-08
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 0.917 29 0 1999 2017
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
cytochrome P450 family 19 subfamily A member 1 0.482 0.690 8.6E-06
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 1.000 27 0 1997 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR
progesterone receptor 0.467 0.690 7.2E-02
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 0.971 25 0 1988 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.365 0.828 0.90
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
group 0.400 1.000 23 0 1992 2014