Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.300 Biomarker CTD_human Post-treatment with S14080 dose-dependently antagonized the hyperalgesia induced by prostaglandin E2, bradykinin, dopamine and by the hyperalgesic cytokines reported to be released by carrageenin (tumour necrosis factor alpha, interleukin-1 and interleukin-8).3. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.400 Biomarker CTD_human Neutrophil adhesion to endothelial cells and factors affecting adhesion in patients with Behçet's disease. 8712863

1996
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.330 Biomarker CTD_human A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. 9403216

1997
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker CTD_human A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. 9403216

1997
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.300 Biomarker CTD_human Moreover, rolipram significantly potentiated hyperalgesia induced by carrageenan, bradykinin, TNF alpha, IL-1 beta, IL-6 and IL-8. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.330 Biomarker CTD_human Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistant Staphylococcus aureus infection. 10910440

2000
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0002965
Disease: Angina, Unstable
Angina, Unstable 		0.300 Biomarker CTD_human In unstable angina pectoris increased plasma IL-8 levels were evidenced in 25 of the 35 patients, after an average interval of 20 +/- 1.2 hours from the last spontaneous episode of angina pectoris. 10660968

2000
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0086666
Disease: Myocardial Preinfarction Syndrome
Myocardial Preinfarction Syndrome 		0.300 Biomarker CTD_human Increased plasma levels of interleukin-8 in patients with unstable angina pectoris. 10660968

2000
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker CTD_human Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistant Staphylococcus aureus infection. 10910440

2000
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0030805
Disease: Bullous pemphigoid
Bullous pemphigoid 		0.310 Biomarker CTD_human The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone. 11359455

2001
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0030200
Disease: Pain, Intractable
Pain, Intractable 		0.300 Biomarker CTD_human Intrathecal methylprednisolone for postherpetic neuralgia. 11280320

2001
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0032768
Disease: Postherpetic neuralgia
Postherpetic neuralgia 		0.300 Biomarker CTD_human Intrathecal methylprednisolone for postherpetic neuralgia. 11280320

2001
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.400 Biomarker CTD_human (1) The expression of IL-1beta mRNA and IL-8 mRNA was increased significantly in patients with UC, as compared with that in the control specimens (P < 0.05) and had a significant positive correlation with NF-kappaB DNA binding activity (r = 0.8363, P < 0.05; r = 0.6024, P < 0.05, respectively). 12133438

2002