Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.300 Therapeutic CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.300 Biomarker CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Therapeutic CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.400 Biomarker CTD_human (1) The expression of IL-1beta mRNA and IL-8 mRNA was increased significantly in patients with UC, as compared with that in the control specimens (P < 0.05) and had a significant positive correlation with NF-kappaB DNA binding activity (r = 0.8363, P < 0.05; r = 0.6024, P < 0.05, respectively). 12133438

2002
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.340 Biomarker CTD_human IL-8 and G-CSF levels in BAL fluid correlate only with the percentage and the absolute number of neutrophils of the BAL fluid in patients with PF (p = 0.02/p = 0.01; p = 0.01/p = 0.01; respectively). 17894541

2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.400 Biomarker CTD_human Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. 18307536

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.330 Biomarker CTD_human A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. 9403216

1997
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker CTD_human A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. 9403216

1997
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.400 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.400 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0334588
Disease: Giant Cell Glioblastoma
Giant Cell Glioblastoma 		0.300 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1527352
Disease: Hepatic Form of Wilson Disease
Hepatic Form of Wilson Disease 		0.300 Biomarker CTD_human A study of oxidative stress, cytokines and glutamate in Wilson disease and their asymptomatic siblings. 25002079

2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1527303
Disease: Chronic Airflow Obstruction
Chronic Airflow Obstruction 		0.300 Biomarker CTD_human Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A. 23099361

2013
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0013604
Disease: Edema
Edema 		0.300 Biomarker CTD_human Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. 19874808

2010
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0151603
Disease: Anasarca
Anasarca 		0.300 Biomarker CTD_human Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. 19874808

2010
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 Biomarker CTD_human Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: a possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors. 15387324

2004
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.400 Biomarker CTD_human Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. 19192274

2009
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0162848
Disease: Lichenoid Eruptions
Lichenoid Eruptions 		0.300 Biomarker CTD_human Association between oral lichenoid reactions and amalgam restorations. 18393961

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.400 Biomarker CTD_human Autocrine production of interleukin-8 confers cisplatin and paclitaxel resistance in ovarian cancer cells. 21742513

2011
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.400 Biomarker CTD_human Autocrine production of interleukin-8 confers cisplatin and paclitaxel resistance in ovarian cancer cells. 21742513

2011
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.400 Biomarker CTD_human Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. 26037280

2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 Biomarker CTD_human Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. 26037280

2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0151468
Disease: Thyroid Gland Follicular Adenoma
Thyroid Gland Follicular Adenoma 		0.300 Biomarker CTD_human Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. 26037280

2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.300 Biomarker CTD_human Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. 21224055

2011