Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0023212
Disease: Left-Sided Heart Failure
Left-Sided Heart Failure
0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0029172
Disease: Oral Submucous Fibrosis
Oral Submucous Fibrosis
0.300 Biomarker CTD_human Inhibitory effect of GMI, an immunomodulatory protein from Ganoderma microsporum, on myofibroblast activity and proinflammatory cytokines in human fibrotic buccal mucosal fibroblasts. 28984080

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0036118
Disease: Salmonella Infections, Animal
Salmonella Infections, Animal
0.300 Biomarker CTD_human Impact of cadmium exposure on swine enterocytes. 29421334

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0235527
Disease: Heart Failure, Right-Sided
Heart Failure, Right-Sided
0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0876994
Disease: Cardiotoxicity
Cardiotoxicity
0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1959583
Disease: Myocardial Failure
Myocardial Failure
0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1961112
Disease: Heart Decompensation
Heart Decompensation
0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence
0.300 Biomarker CTD_human MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD. 28864214

2017

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0040332
Disease: Tobacco Dependence
Tobacco Dependence
0.300 Biomarker CTD_human MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD. 28864214

2017

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.300 Biomarker CTD_human MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD. 28864214

2017

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1527303
Disease: Chronic Airflow Obstruction
Chronic Airflow Obstruction
0.300 Biomarker CTD_human MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD. 28864214

2017

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0524610
Disease: Chronic Alcoholic Hepatitis
Chronic Alcoholic Hepatitis
0.300 Biomarker CTD_human Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease. 26220752

2016

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0151468
Disease: Thyroid Gland Follicular Adenoma
Thyroid Gland Follicular Adenoma
0.300 Biomarker CTD_human Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. 26037280

2015

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0019202
Disease: Hepatolenticular Degeneration
Hepatolenticular Degeneration
0.300 Biomarker CTD_human The serum IL6 {median (IQRs), 9.42(10.92) vs. 5.2(5.34) pg/ml; P=0.001}, IL8 {12.37(10.92) vs. 5.63(5.52) pg/ml; P<0.001}, IL10 {8.33(8.3) vs. 2.05(1.37) pg/ml; P=0.001} and TNFα {6.14(8.95) vs. 3.61(3.58) pg/ml; P<0.001} were also increased in WD patients compared to controls. 25002079

2014

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0155862
Disease: Streptococcal pneumonia
Streptococcal pneumonia
0.300 Biomarker CTD_human Role of SIRT1 in Streptococcus pneumoniae-induced human β-defensin-2 and interleukin-8 expression in A549 cell. 24894820

2014

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0345967
Disease: Malignant mesothelioma
Malignant mesothelioma
0.300 Biomarker CTD_human Increased levels of C-C chemokine RANTES in asbestos exposed workers and in malignant mesothelioma patients from an hyperendemic area. 25162674

2014

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1527352
Disease: Hepatic Form of Wilson Disease
Hepatic Form of Wilson Disease
0.300 Biomarker CTD_human A study of oxidative stress, cytokines and glutamate in Wilson disease and their asymptomatic siblings. 25002079

2014

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0015404
Disease: Eye Infections, Bacterial
Eye Infections, Bacterial
0.300 Biomarker CTD_human Resveratrol role in Staphylococcus aureus-induced corneal inflammation. 23661603

2013

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1318973
Disease: Staphylococcus aureus infection
Staphylococcus aureus infection
0.300 Biomarker CTD_human Resveratrol role in Staphylococcus aureus-induced corneal inflammation. 23661603

2013

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C1527303
Disease: Chronic Airflow Obstruction
Chronic Airflow Obstruction
0.300 Biomarker CTD_human Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A. 23099361

2013

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0007621
Disease: Neoplastic Cell Transformation
Neoplastic Cell Transformation
0.300 Biomarker CTD_human Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells. 22015448

2012

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.300 Biomarker CTD_human Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. 21224055

2011

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0013604
Disease: Edema
Edema
0.300 Biomarker CTD_human Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. 19874808

2010

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0086540
Disease: Leishmaniasis, New World
Leishmaniasis, New World
0.300 Biomarker CTD_human Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors. 20102417

2010

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0086541
Disease: Urban cutaneous leishmaniasis
Urban cutaneous leishmaniasis
0.300 Biomarker CTD_human Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors. 20102417

2010