Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.300 Biomarker RGD TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. 15781474

2005

Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes. 16630594

2006

Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes. 16630594

2006

Entrez Id: 104
Gene Symbol: ADARB1
ADARB1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD ADAR2-dependent RNA editing of AMPA receptor subunit GluR2 determines vulnerability of neurons in forebrain ischemia. 16504947

2006

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Modulation of RAGE isoforms expression in the brain and plasma of rats exposed to transient focal cerebral ischemia. 22528836

2012

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia. 21934531

2011

Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. 14526224

2003

Entrez Id: 286
Gene Symbol: ANK1
ANK1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Distribution of ankyrin isoforms and their proteolysis after ischemia and reperfusion in rat brain. 9202331

1997

Entrez Id: 287
Gene Symbol: ANK2
ANK2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Distribution of ankyrin isoforms and their proteolysis after ischemia and reperfusion in rat brain. 9202331

1997

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.240 Biomarker RGD Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke. 19623195

2009

Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Rapamycin alleviates brain edema after focal cerebral ischemia reperfusion in rats. 24773551

2014

Entrez Id: 1386
Gene Symbol: ATF2
ATF2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Persistent phosphorylation of cyclic AMP responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain. 10077326

1999

Entrez Id: 1386
Gene Symbol: ATF2
ATF2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury. 9813301

1998

Entrez Id: 506
Gene Symbol: ATP5F1B
ATP5F1B
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers. 21950801

2011

Entrez Id: 23621
Gene Symbol: BACE1
BACE1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Increased beta-secretase activity and expression in rats following transient cerebral ischemia. 15120577

2004

Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia. 21167243

2011

Entrez Id: 27113
Gene Symbol: BBC3
BBC3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. 12913114

2003

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. 22509406

2012

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD The antibiotic erythromycin induces tolerance against transient global cerebral ischemia in rats (pharmacologic preconditioning). 16732092

2006

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia. 18083315

2008

Entrez Id: 599
Gene Symbol: BCL2L2
BCL2L2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Overexpression of the cell death suppressor Bcl-w in ischemic brain: implications for a neuroprotective role via the mitochondrial pathway. 10724126

2000

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. 22509406

2012

Entrez Id: 27018
Gene Symbol: BEX3
BEX3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat. 11124986

2000

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus. 14972662

2004

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.500 Therapeutic RGD The protective effect of SCR(15-18) on cerebral ischemia-reperfusion injury. 22004711

2011