Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.993 137 0 2002 2020
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3
solute carrier family 12 member 3 0.493 0.808 3.0E-32
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.970 33 0 1990 2019
Entrez Id: 54997
Gene Symbol: TESC
TESC
tescalcin 0.570 0.692 0.11
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.970 33 0 1990 2019
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
polycystin 1, transient receptor potential channel interacting 0.493 0.769 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 1.000 15 1 1994 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.917 12 0 2003 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.917 12 1 2003 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.917 12 0 2003 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.100 None 0.917 12 2 2003 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.080 None 0.875 8 0 2009 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.070 None 1.000 7 0 2004 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.070 None 0.857 7 0 1996 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.435 0.808 0.99
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.060 None 1.000 6 0 2004 2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.050 None 1.000 5 0 2007 2019
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
RAS p21 protein activator 1 0.481 0.885 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.040 None 1.000 4 0 2003 2016
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.040 None 0.750 4 0 2004 2011
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
ribosomal protein S6 kinase B1 0.511 0.731 0.97
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.050 None 1.000 4 0 2006 2019
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
8-oxoguanine DNA glycosylase 0.453 0.808 3.9E-12
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.040 None 1.000 3 0 2008 2010
Entrez Id: 54541
Gene Symbol: DDIT4
DDIT4
DNA damage inducible transcript 4 0.576 0.769 6.8E-04
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.040 None 1.000 3 0 2005 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2014 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1 0.453 0.846 0.14
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2010 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 0.363 0.846
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2013 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2011 2020
Entrez Id: 2688
Gene Symbol: GH1
GH1
growth hormone 1 0.373 0.923 3.0E-02
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2005 2018
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2 0.456 0.846 3.5E-08
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2010 2017
Entrez Id: 51256
Gene Symbol: TBC1D7
TBC1D7
TBC1 domain family member 7 0.729 0.385 2.9E-12
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis
disease 0.030 None 1.000 3 0 2013 2018