| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
disease | 1.000 | definitive | 0.980 | 384 | 23 | 1994 | 2020 | ||||||||
|
TSC complex subunit 1 | 0.440 | 0.808 | 1.00 |
|
disease | 0.900 | definitive | 0.981 | 310 | 6 | 1990 | 2020 | ||||||||
|
eukaryotic translation initiation factor 4E binding protein 1 | 0.494 | 0.885 | 0.21 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2002 | 2011 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.993 | 137 | 0 | 2002 | 2020 | ||||||||
|
tescalcin | 0.570 | 0.692 | 0.11 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1990 | 2019 | ||||||||
|
solute carrier family 12 member 3 | 0.493 | 0.808 | 3.0E-32 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1990 | 2019 | ||||||||
|
polycystin 1, transient receptor potential channel interacting | 0.493 | 0.769 | 1.00 |
|
disease | 0.100 | None | 1.000 | 15 | 1 | 1994 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 2003 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 2003 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.917 | 12 | 1 | 2003 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.917 | 12 | 2 | 2003 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.080 | None | 0.875 | 8 | 0 | 2009 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2004 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 1996 | 2019 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2004 | 2017 | ||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2007 | 2019 | ||||||||
|
ribosomal protein S6 kinase B1 | 0.511 | 0.731 | 0.97 |
|
disease | 0.050 | None | 1.000 | 4 | 0 | 2006 | 2019 | ||||||||
|
RAS p21 protein activator 1 | 0.481 | 0.885 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2003 | 2016 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2004 | 2011 | ||||||||
|
DNA damage inducible transcript 4 | 0.576 | 0.769 | 6.8E-04 |
|
disease | 0.040 | None | 1.000 | 3 | 0 | 2005 | 2014 | ||||||||
|
8-oxoguanine DNA glycosylase | 0.453 | 0.808 | 3.9E-12 |
|
disease | 0.040 | None | 1.000 | 3 | 0 | 2008 | 2010 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2014 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2009 | 2019 | ||||||||
|
growth hormone 1 | 0.373 | 0.923 | 3.0E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2005 | 2018 | ||||||||
|
protein kinase D1 | 0.531 | 0.846 | 6.6E-07 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1997 | 2014 |