Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Our findings indicate a potentially novel strategy for the treatment of colon cancer, one that targets CK2 simultaneous with TNF-alpha administration. 12842827

2003

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 14507667

2003

Entrez Id: 6714
Gene Symbol: SRC
SRC
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway. 14569062

2004

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway. 14569062

2004

Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.370 Biomarker CTD_human Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway. 14569062

2004

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.320 Biomarker CTD_human In our present study, we investigated the potential role of WT1 gene in human colon cancer. 14961577

2004

Entrez Id: 5608
Gene Symbol: MAP2K6
MAP2K6
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.320 Therapeutic CTD_human Analysis of an additional two human colon cancer cell lines with and without K-ras mutation also showed a K-ras- and VDR-dependent toxicity of MKK6. 15037631

2004

Entrez Id: 3481
Gene Symbol: IGF2
IGF2
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. 15057734

2004

Entrez Id: 894
Gene Symbol: CCND2
CCND2
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.610 Biomarker CTD_human For example, genes involved in inflammation and matrix proteases and a cell cycle regulator gene, cyclin D2, were highly expressed in colon cancers. 15059925

2004

Entrez Id: 30011
Gene Symbol: SH3KBP1
SH3KBP1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 4316
Gene Symbol: MMP7
MMP7
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Interestingly, a subset of genes whose expression is characteristic of Paneth cells, i.e. the defensins and matrilysin, were highly overexpressed in colon cancers. 15059925

2004

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.360 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 430
Gene Symbol: ASCL2
ASCL2
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.350 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 6280
Gene Symbol: S100A9
S100A9
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.340 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.330 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 5268
Gene Symbol: SERPINB5
SERPINB5
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 6876
Gene Symbol: TAGLN
TAGLN
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 6817
Gene Symbol: SULT1A1
SULT1A1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004

Entrez Id: 2949
Gene Symbol: GSTM5
GSTM5
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.300 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004