Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7590720
rs7590720
MREG ; PECR
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.800 GeneticVariation GWASDB Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs7590720
rs7590720
MREG ; PECR
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.800 GeneticVariation GWASCAT Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs1800973
rs1800973
LYZ
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs12392447
rs12392447
RN7SL697P
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs10913569
rs10913569
C1orf220
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A genome-wide association study of alcohol dependence. 20202923

2010
dbSNP: rs6777876
rs6777876
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.800 GeneticVariation GWASCAT Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. 21314694

2011
dbSNP: rs6777876
rs6777876
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.800 GeneticVariation GWASDB Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. 21314694

2011
dbSNP: rs9556711
rs9556711
MBNL2
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. 21529783

2011
dbSNP: rs9512637
rs9512637
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.700 GeneticVariation GWASCAT A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. 21529783

2011
dbSNP: rs8040009
rs8040009
C15orf32
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		T 0.700 GeneticVariation GWASCAT A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. 21529783

2011
dbSNP: rs6716455
rs6716455
LINC01818
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. 21529783

2011
dbSNP: rs750338
rs750338
PKNOX2
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.810 GeneticVariation GWASDB The top hit of PKNOX2 (rs750338 with p=1.47 × 10(-6)) in the meta-analysis was replicated with the Australian Twin-Family Study of 778 families (p=1.39 × 10(-2)) Furthermore, several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample (top SNPs were rs2269655, rs856613, and rs10496768 with p=4.58 × 10(-3), 2.1 × 10(-4), and 2.86 × 10(-3) for KIAA0040, NRD1 and THSD7B, respectively). 21703634

2011
dbSNP: rs750338
rs750338
PKNOX2
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.810 GeneticVariation GWASCAT The top hit of PKNOX2 (rs750338 with p=1.47 × 10(-6)) in the meta-analysis was replicated with the Australian Twin-Family Study of 778 families (p=1.39 × 10(-2)) Furthermore, several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample (top SNPs were rs2269655, rs856613, and rs10496768 with p=4.58 × 10(-3), 2.1 × 10(-4), and 2.86 × 10(-3) for KIAA0040, NRD1 and THSD7B, respectively). 21703634

2011
dbSNP: rs6701037
rs6701037
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.800 GeneticVariation GWASCAT A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs6701037
rs6701037
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.800 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs6425323
rs6425323
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs1869324
rs1869324
THSD7B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs1057302
rs1057302
KIAA0040
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs9458121
rs9458121
MAP3K4
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs7607774
rs7607774
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs6778524
rs6778524
PLCL2
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs3773165
rs3773165
SLC6A6
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs12489456
rs12489456
SLC6A6
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs11623335
rs11623335
TMEM260
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs1789891
rs1789891
ADH1B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.820 GeneticVariation GWASDB Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. 22004471

2012