Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1000579
rs1000579
STX18-AS1
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.800 GeneticVariation GWASDB Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. 22004471

2012
dbSNP: rs1000579
rs1000579
STX18-AS1
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.800 GeneticVariation GWASCAT Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. 28714907

2017
dbSNP: rs1000579
rs1000579
STX18-AS1
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.800 GeneticVariation GWASCAT Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. 22004471

2012
dbSNP: rs10196867
rs10196867
CTNNA2
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.710 GeneticVariation GWASCAT We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P<sub>meta</sub> = 3.60 × 10<sup>-9</sup>), AGBL4 rs147247472 (P<sub>meta</sub> = 3.40 × 10<sup>-12</sup>), and CTNNA2 rs10196867 (P<sub>meta</sub> = 4.73 × 10<sup>-9</sup>). 31462767

2019
dbSNP: rs10198241
rs10198241
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344

2017
dbSNP: rs10211296
rs10211296
CSRNP3
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASCAT Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors. 28990359

2017
dbSNP: rs10392
rs10392
PPP1R16B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		A 0.700 GeneticVariation GWASCAT Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. 28714907

2017
dbSNP: rs10483038
rs10483038
KCNJ6
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs1057302
rs1057302
KIAA0040
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs10913569
rs10913569
C1orf220
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A genome-wide association study of alcohol dependence. 20202923

2010
dbSNP: rs11066001
rs11066001
BRAP
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison. 31591379

2019
dbSNP: rs11075992
rs11075992
FTO
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813

2019
dbSNP: rs111372083
rs111372083
KCNJ6
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs111576572
rs111576572
KCNJ6
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs115357105
rs115357105
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344

2017
dbSNP: rs1154433
rs1154433
ADH1B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813

2019
dbSNP: rs115460205
rs115460205
FSTL5
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASCAT Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors. 28990359

2017
dbSNP: rs11583322
rs11583322
STK40
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Dosage transmission disequilibrium test (dTDT) for linkage and association detection. 23691058

2013
dbSNP: rs11623335
rs11623335
TMEM260
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs11681792
rs11681792
NRXN1
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		A 0.700 GeneticVariation GWASCAT A genome-wide association study of behavioral disinhibition. 23942779

2013
dbSNP: rs11825659
rs11825659
IGSF9B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344

2017
dbSNP: rs11922615
rs11922615
SETD5
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. 22096494

2011
dbSNP: rs12006002
rs12006002
ADAMTSL1
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013
dbSNP: rs12180309
rs12180309
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344

2017
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.900 GeneticVariation GWASDB In case-control analysis, ADH1B rs1229984 (H47R) showed the most significant association with the risk of AD (p = 2.63 × 10(-21), OR = 2.35). 23456092

2013