Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The obesity risk alleles of BDNF rs925946 and FTO rs9939609 were related to a lower calcium intake (P = .001 and .037). 26162542

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A region in the first intron of the fat mass- and obesity-associated (FTO) gene, encompassing markers rs9939973, rs8050136, and rs9939609, has been consistently associated with obesity and body mass index (BMI) in different populations. 26529281

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A minimal gata2 promoter-GFP cassette was inserted 1.3 kb upstream of the obesity associated SNP rs9939609 in a human FTO BAC plasmid. 26271004

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE This paper describes a bio-microfluidic platform coupled to a non-cross-linking colorimetric gold nanoprobe assay to detect a single nucleotide polymorphism associated with increased risk of obesity fat-mass and obesity-associated (FTO) rs9939609 (Carlos et al., 2014). 25765286

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE FTO rs9939609 polymorphism is associated with the increased risk of obesity among children and adolescents, especially the homozygous carriers. 25753879

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The effects of exercise combined with dietary intervention on obesity were associated with the FTO rs9939609 polymorphism in chinese adolescents and children. 26698254

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Recently, our team reported that the fat mass and obesity-associated (FTO) gene rs9939609 obesity-risk variant is paradoxically inversely associated with the risk of depression. 26717541

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Therefore, the present study aimed to evaluate the relationships among the gene polymorphisms ghrelin (GHRL-rs26802), ghrelin receptor (GHSR-rs572169), leptin (LEP-rs7799039), leptin receptor (LEPR-rs1137101) and fat mass and obesity-associated (FTO-rs9939609) and obesity. 26255942

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The obesity risk allele at FTO SNP rs9939609 was not associated with BMI-SDS reduction during the lifestyle intervention (p = 0.622), but with weight regain 1 year after end of the intervention in multiple linear regression analyses adjusted for age, sex, pubertal stage, and baseline BMI-SDS (Bonferroni corrected p = 0.002). 24819256

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The minor A-allele of the FTO variant rs9939609 was associated with increased risk of obesity (OR 1.15, 95% CI 1.08-1.21, p = 2.14 × 10(-) (5) ), BMI (β = 0.30 kg/m2, 95% CI 0.21-0.38, p = 4.78 × 10(-) (11) ) and other regional adiposity measurements [waist (β = 0.74 cm, 95% CI 0.49-0.99), HC (β = 0.52, 95% CI 0.26-0.78), and waist-hip ratio (WHR) (β = 0.002, 95% CI 0.001-0.004)] in Indians (p ≤ 0.001). 23963770

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Therefore, the present study aimed to examine the relationships between FTO rs9939609 and the MC4R rs17782313 with REE, leptin, ghrelin and thyrotropin levels in obese women. 24307561

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE These findings indicate the genetic variation of rs9939609 is associated with obesity and dietary preferences in Chinese children and adolescents. 25110886

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A dose-response relationship was found between the number of risk alleles in rs7206790, rs11644943 and rs9939609 and the risk of obesity. 25251416

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Association of obesity with rs1421085 and rs9939609 polymorphisms of FTO gene. 25074273

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Our aim was to identify whether the obesity-susceptible gene variants (rs9939609, rs9930506, and rs4783819 in fat mass and obesity-associated gene (FTO); rs12970134 and rs17782313 in melanocortin-4 receptor gene (MC4R); and rs7566605, rs13428113, and rs9308762 in insulin-induced gene 2 [INSIG2]) were associated with NAFLD. 24458218

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The A allele of rs9939609 in the FTO gene predisposes to increased body mass index (BMI) and obesity. 25265168

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The associations of FTO rs9939609 with BMI and obesi</span>ty did not appear until children reached 12-14 years. 24827155

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE In the meta-analysis of 42 studies for 11 obesity/BMI-associated loci, we observed a statistically significant association of the FTO rs9939609 polymorphism (66 425 T2D cases/239 689 normoglycaemic subjects; P = 1·00 × 10(-41) ) and six other variants with T2D risk (17 915 T2D cases/27 531 normoglycaemic individuals: n = 40 629-130 001; all P < 0·001 for SH2B1 rs7498665, FAIM2 rs7138803, TMEM18 rs7561317, GNPDA2 rs10938397, BDNF rs925946 and NEGR1 rs2568958). 24528214

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis. 25377722

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The risk alleles for obesity ("A" allele for the rs9939609 FTO variant and "G" allele for the rs9930506 FTO variant) were associated with low weight at birth. 25539997

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma 2 gene (PPARG2) rs1801282 polymorphisms are type 2 diabetes mellitus susceptibility gene variants associated with obesity. 24969838

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE In the present study, we examined the association between variants in fat mass- and obesity-associated [rs9939609 (A/T)], melanocortin 4 receptor [rs17782313 (C/T), and rs12970134 (A/G)], SLC30A8 [rs13266634 (C/T)], and a member of the potassium voltage-gated channels [rs2237892(C/T)] genes in diabetes patients from Saudi Arabia. 25501231

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE The Fat Mass and Obesity-Associated Protein (FTO) gene rs9939609 single nucleotide polymorphism (SNP) has been associated with obesity, metabolic syndrome, insulin resistance (IR), and type 2 diabetes mellitus in the general population. 25367448

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE We confirmed two FTO SNPs (rs62048402 and rs9939609) had nominal significant effects on BMI or obesity. 24956226

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Our findings indicate that rs9939609 in the FTO gene is associated with pancreatic cancer risk in Japanese subjects, possibly through a mechanism that is independent of obesity. 23835106

2013