Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.900 0.936 289 13 1991 2017
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.700 0.940 390 3 2008 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.700 0.953 133 2 1997 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.600 0.935 112 2 1994 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.600 1.000 44 2 2005 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 300 0.438 0.759 8.2E-03 0.600 0.952 21 0 1995 2013
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.600 1.000 15 0 1995 2016
Entrez Id: 3020
Gene Symbol: H3F3A
H3F3A
P84243 H3 histone family member 3A nucleic acid binding 30 0.667 0.310 0.13 0.600 1.000 14 0 2012 2016
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 enzyme modulator 308 0.458 0.724 1.00 0.600 1.000 13 0 1994 2015
Entrez Id: 8358
Gene Symbol: HIST1H3B
HIST1H3B
P68431 histone cluster 1 H3 family member b nucleic acid binding 8 0.785 0.069 1.5E-05 0.520 1.000 3 1 2012 2016
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 kinase; receptor; transferase 102 0.573 0.552 0.38 0.510 1.000 3 0 2014 2014
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.500 0.980 55 5 2004 2018
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
Q9NZ71 regulator of telomere elongation helicase 1 nucleic acid binding 213 0.509 0.621 1.6E-08 0.500 1.000 22 3 2009 2017
Entrez Id: 23187
Gene Symbol: PHLDB1
PHLDB1
Q86UU1 pleckstrin homology like domain family B member 1 9 0.785 0.207 9.8E-02 0.500 1.000 14 5 2009 2017
Entrez Id: 137196
Gene Symbol: CCDC26
CCDC26
Q8TAB7 CCDC26 long non-coding RNA 32 0.713 0.310 0.500 1.000 11 3 2009 2018
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin nucleic acid binding 214 0.502 0.759 2.6E-16 0.410 1.000 1 1 2016 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.973 231 3 1987 2018
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.400 0.979 148 3 1991 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.983 62 0 1993 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 1.000 40 0 1998 2018
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 signaling molecule 437 0.404 0.897 1.9E-02 0.400 0.943 36 0 1990 2017
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 0.963 34 0 1999 2014
Entrez Id: 546
Gene Symbol: ATRX
ATRX
P46100 ATRX, chromatin remodeler 283 0.489 0.690 1.00 0.400 0.958 26 0 2013 2018
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 264 0.449 0.828 4.8E-09 0.400 0.952 23 7 2008 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene nucleic acid binding 436 0.396 0.759 1.00 0.400 1.000 22 0 1995 2017