Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 34 2 1998 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.100 None 1.000 22 0 1994 2019
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 365 0.430 0.885 0.90 0.100 None 1.000 22 0 1989 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.400 None 1.000 20 0 1995 2020
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
P28908 TNF receptor superfamily member 8 301 0.444 0.808 0.86 0.100 None 1.000 20 0 1988 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 1.000 17 1 1989 2019
Entrez Id: 3492
Gene Symbol: IGH
IGH
immunoglobulin heavy locus 238 0.473 0.654 0.100 None 1.000 17 0 1996 2016
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 321 0.459 0.808 8.9E-10 0.100 None 1.000 14 0 1995 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 12 0 2017 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 12 0 2001 2015
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.100 None 1.000 12 0 1992 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 11 0 2012 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 1.000 11 0 1990 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 11 0 1995 2018
Entrez Id: 4049
Gene Symbol: LTA
LTA
P01374 lymphotoxin alpha Signaling 353 0.434 0.885 0.20 0.100 None 1.000 10 4 1998 2014
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.390 None 1.000 9 1 1999 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.080 None 1.000 8 1 2006 2017
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
P06748 nucleophosmin 1 Chaperone 283 0.464 0.846 1.00 0.380 None 1.000 8 0 1994 2008
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.070 None 1.000 7 1 2004 2019
Entrez Id: 846
Gene Symbol: CASR
CASR
P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.060 None 1.000 6 0 2017 2019
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 318 0.448 0.846 3.5E-08 0.060 None 1.000 6 0 2017 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.060 None 1.000 6 0 2013 2019
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.060 None 1.000 6 1 1999 2019
Entrez Id: 1525
Gene Symbol: CXADR
CXADR
P78310 CXADR Ig-like cell adhesion molecule 305 0.454 0.885 0.37 0.060 None 1.000 6 0 2017 2019
Entrez Id: 951
Gene Symbol: CD37
CD37
P11049 CD37 molecule 40 0.647 0.462 4.4E-06 0.060 None 1.000 6 0 2014 2018