Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 2001 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.020 None 1.000 2 0 2017 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 1.000 6 1 2007 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2011 2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.060 None 1.000 6 0 2001 2014
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 0 2001 2001
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.050 None 0.800 5 0 2015 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.040 None 1.000 4 0 2000 2013
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.020 None 1.000 2 0 2014 2016
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.220 None 1.000 5 0 1991 2015
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		P04439 major histocompatibility complex, class I, A 672 0.370 0.846 1.3E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 644 0.372 0.846 0.71 0.020 None 1.000 2 0 2014 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.020 None 1.000 2 0 2014 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.010 None 1.000 1 0 2004 2004
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.010 None 1.000 1 0 1998 1998