Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.941 20 0 1994 2014
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.550 1.000 6 0 2012 2017
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 237 0.469 0.655 0.87 0.550 1.000 6 0 2012 2017
Entrez Id: 54894
Gene Symbol: RNF43
RNF43
Q68DV7 ring finger protein 43 47 0.648 0.276 0.57 0.500 1 0 2012 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 1.000 21 0 2002 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 1.000 18 0 2000 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 17 1 2002 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 1.000 14 0 1990 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.400 0.800 12 0 1993 2013
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.350 1.000 5 0 2003 2015
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 665 0.398 0.759 1.00 0.340 1.000 5 0 2014 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.340 1.000 5 0 2006 2016
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.310 1.000 3 0 2014 2015
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 394 0.443 0.793 0.71 0.310 2 0 2007 2012
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 531 0.385 0.931 1.5E-14 0.310 1.000 2 0 2001 2006
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.310 1.000 2 0 2006 2012
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 73 0.590 0.517 1.00 0.310 1.000 2 0 2014 2018
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin extracellular matrix protein 86 0.565 0.483 8.2E-23 0.310 1.000 2 0 2003 2013
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Q92911 solute carrier family 5 member 5 transporter 157 0.524 0.759 2.9E-03 0.310 1.000 1 0 2007 2007
Entrez Id: 5774
Gene Symbol: PTPN3
PTPN3
P26045 protein tyrosine phosphatase, non-receptor type 3 29 0.685 0.414 3.2E-09 0.310 1.000 1 0 2014 2014
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 211 0.505 0.724 1.00 0.300 1 0 2014 2014
Entrez Id: 6092
Gene Symbol: ROBO2
ROBO2
Q9HCK4 roundabout guidance receptor 2 24 0.701 0.241 1.00 0.300 1 0 2012 2012
Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
P17612 protein kinase cAMP-activated catalytic subunit alpha 75 0.616 0.552 0.99 0.300 1 0 2016 2016
Entrez Id: 5178
Gene Symbol: PEG3
PEG3
Q9GZU2 paternally expressed 3 transcription factor 42 0.645 0.414 2.2E-05 0.300 1 0 2012 2012
Entrez Id: 58508
Gene Symbol: KMT2C
KMT2C
Q8NEZ4 lysine methyltransferase 2C 60 0.604 0.621 1.00 0.300 1 0 2012 2012