Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.886 79 1 1992 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.100 0.903 72 0 1988 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.100 0.824 51 2 2004 2017
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
P49767 vascular endothelial growth factor C signaling molecule 168 0.501 0.690 0.51 0.100 0.938 48 0 2000 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.100 0.956 45 1 1990 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.100 0.917 36 1 1998 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.100 1.000 31 0 1996 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.100 0.903 31 0 1990 2017
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 474 0.391 0.897 1.4E-02 0.100 0.917 24 0 2003 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1
P15531 NME/NM23 nucleoside diphosphate kinase 1 242 0.470 0.759 3.1E-03 0.100 0.870 23 5 1991 2013
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.100 1.000 21 0 1995 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 0.762 21 0 1994 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.100 0.950 20 0 2005 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.100 0.889 18 0 1994 2017
Entrez Id: 1236
Gene Symbol: CCR7
CCR7
P32248 C-C motif chemokine receptor 7 193 0.477 0.759 5.3E-02 0.100 0.944 18 0 2002 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor nucleic acid binding; receptor; transcription factor 230 0.467 0.690 7.2E-02 0.100 0.944 18 0 1999 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.100 1.000 15 1 1995 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 400 0.407 0.759 0.100 0.867 15 0 2008 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.100 1.000 14 1 2007 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.100 0.786 14 0 1998 2014
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha signaling molecule 274 0.456 0.828 1.4E-02 0.100 0.923 13 0 1986 2016
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 336 0.429 0.828 9.3E-02 0.100 0.923 13 0 1995 2016
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene 452 0.418 0.724 1.00 0.100 1.000 13 3 1996 2017
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 350 0.421 0.724 0.13 0.100 1.000 12 0 2005 2017
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
P35916 fms related tyrosine kinase 4 153 0.510 0.724 1.00 0.100 0.818 11 0 2001 2014