Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker disease BEFREE Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis. 28408323 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 Biomarker disease BEFREE Human apolipoprotein E (ApoE) is associated with high cholesterol levels, coronary artery disease, and especially Alzheimer's disease. 29202360 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 Biomarker disease BEFREE The apolipoprotein E (apoE) gene has been implicated in various conditions, most notably Alzheimer's disease and coronary artery disease. 28299413 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.500 GeneticVariation disease BEFREE Published studies indicated that the MTHFR gene polymorphisms C677T and A1298C are associated with congenital heart disease (CHD) risk in children, but obtained inconsistent results. 29554656 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 AlteredExpression disease BEFREE Significance of lipoprotein(a) levels in familial hypercholesterolemia and coronary artery disease. 28351002 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation disease BEFREE Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. 28566218 2018
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
0.500 GeneticVariation disease GWASCAT Darapladib, a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, failed to demonstrate efficacy for the primary endpoints in two large phase III cardiovascular outcomes trials, one in stable coronary heart disease patients (STABILITY) and one in acute coronary syndrome (SOLID-TIMI 52). 28753643 2017
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
0.500 GeneticVariation disease BEFREE Darapladib, a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, failed to demonstrate efficacy for the primary endpoints in two large phase III cardiovascular outcomes trials, one in stable coronary heart disease patients (STABILITY) and one in acute coronary syndrome (SOLID-TIMI 52). 28753643 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 GeneticVariation disease BEFREE ApoE gene polymorphism and its relationship with coronary artery disease in ethnic Kashmiri population. 26409839 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation disease GWASCAT Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib. 28753643 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.500 GeneticVariation disease BEFREE A meta-analysis of polymorphism C677T (rs1801133) of the methylene tetrahydrofolate reductase (MTHFR) gene as a potential risk factor for congenital heart disease (CHD) in Chinese paediatric population was studied in view of the previously reported controversial results. 28591039 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 GeneticVariation disease GWASCAT Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib. 28753643 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 GeneticVariation disease BEFREE Association of APOE gene polymorphism with lipid profile and coronary artery disease in Afro-Caribbeans. 28727855 2017
Entrez Id: 338
Gene Symbol: APOB
APOB
0.500 AlteredExpression disease BEFREE We aimed to investigate the cumulative effect of high CRP level and apolipoprotein B-to-apolipoprotein A-1 (ApoB/ApoA-1) ratio on the incidence of ischemic stroke (IS) or coronary heart disease (CHD) in a Mongolian population in China. 27554116 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 GeneticVariation disease BEFREE Apolipoprotein E Gene Variants and Risk of Coronary Heart Disease: A Meta-Analysis. 27868062 2017
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.500 GeneticVariation disease BEFREE Molecular analysis of the LDLR gene in coronary artery disease patients from the Indian population. 26927322 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 GeneticVariation disease BEFREE Study of common variants of the apolipoprotein E and lipoprotein lipase genes in patients with coronary heart disease and variable body mass index. 26188224 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.500 GeneticVariation disease BEFREE MTHFR rs1801131 were identified as loci in Chinese population that were involved in CHD. 26035828 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.500 GeneticVariation disease BEFREE MTHFR C677T is a potential risk factor for CHD in our local residents of Shandong province in China. 26990189 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 Biomarker disease BEFREE The apolipoprotein E gene (APOE) is associated with coronary heart disease and stroke, but the relation with peripheral artery disease (PAD) is unknown. 26800308 2016
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker disease BEFREE Elevated lipoprotein(a), hypertension and renal insufficiency as predictors of coronary artery disease in patients with genetically confirmed heterozygous familial hypercholesterolemia. 26340131 2016
Entrez Id: 338
Gene Symbol: APOB
APOB
0.500 GeneticVariation disease BEFREE Association between apolipoprotein B gene polymorphisms and the risk of coronary heart disease (CHD): an update meta-analysis. 26537298 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
0.500 Biomarker disease BEFREE Meta-analysis for the Association of Apolipoprotein E ε2/ε3/ε4 Polymorphism with Coronary Heart Disease. 25963363 2016
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
0.500 Biomarker disease BEFREE Deciphering the Causal Role of sPLA2s and Lp-PLA2 in Coronary Heart Disease. 26338298 2016
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.500 Biomarker disease BEFREE Familial hypercholesterolemia (FH) is a dominantly inherited disorder characterized by markedly elevated plasma low-density lipoprotein cholesterol and premature coronary heart disease. 26275368 2016