Disease: Pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
ALB P02768 albumin Transporter 0.64 0.317 0.962
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DUOX1 Q9NRD9 dual oxidase 1 Enzyme 6.2E-33 0.570 0.692
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGF7 P21781 fibroblast growth factor 7 Signaling 0.77 0.519 0.846
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923