Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
ASAH2 Q9NR71 N-acylsphingosine amidohydrolase 2 4.3E-03 0.716 0.538
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
BUD13 Q9BRD0 BUD13 homolog 2.1E-06 0.751 0.538
APOA4 P06727 apolipoprotein A4 5.5E-06 0.582 0.577
ACACB O00763 acetyl-CoA carboxylase beta 7.6E-47 0.644 0.654
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
MEF2A Q02078 myocyte enhancer factor 2A Transcription factor 0.99 0.585 0.692
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
ABCG1 P45844 ATP binding cassette subfamily G member 1 Transporter 0.11 0.560 0.692
NR1H3 Q13133 nuclear receptor subfamily 1 group H member 3 Nuclear receptor 0.90 0.566 0.692
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
SCARB1 Q8WTV0 scavenger receptor class B member 1 Receptor 6.6E-02 0.559 0.731
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808