Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
CD40 P25942 CD40 molecule 0.85 0.396 0.846
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
ENG P17813 endoglin 1.00 0.446 0.846