Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
ACACB O00763 acetyl-CoA carboxylase beta 7.6E-47 0.644 0.654
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
APOA4 P06727 apolipoprotein A4 5.5E-06 0.582 0.577
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808