Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ACACB O00763 acetyl-CoA carboxylase beta 7.6E-47 0.644 0.654
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
NOX1 Q9Y5S8 NADPH oxidase 1 8.7E-08 0.536 0.808
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885