rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two mutations (T174M and M235T) in the angiotensinogen gene have been reported to be associated with hypertension.
|
7946168 |
1994 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two mutations (T174M and M235T) in the angiotensinogen gene have been reported to be associated with hypertension.
|
7946168 |
1994 |
rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the whole population blood pressure levels and prevalence of high blood pressure did not vary according to T1</span>74M and M235T genotypes.
|
7622852 |
1995 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The angiotensinogen gene has recently been linked with essential hypertension in affected sibships and a particular polymorphism in exon 2 of the angiotensinogen gene, a threonine to methionine substitution at position 235 (M235T), has been associated with pre-eclampsia and hypertension.
|
8523390 |
1995 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A DNA polymorphism which alters methionine to threonine at position 235 (M235T) within the angiotensinogen peptide has been associated previously with hypertension.
|
7635961 |
1995 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the whole population blood pressure levels and prevalence of high blood pressure did not vary according to T174M and M235T genotypes.
|
7622852 |
1995 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
First, a contingency chi-square analysis was carried out to test for an association between the M235T polymorphism and hypertension status.
|
7649545 |
1995 |
rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, a polymorphism in the angiotensinogen gene substituting methionine for threonine (T174M) has been associated with hypertension in nondiabetic populations.
|
8593944 |
1996 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that the angiotensinogen polymorphism M235T might influence susceptibility to nephropathy in insulin-dependent diabetes, but its effect, if any, is rather small and independent of hypertension.
|
8621207 |
1996 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings do not support the hypothesis that the M235T variant of the angiotensinogen gene is a risk factor for the development of post-transplant hypertension.
|
8856207 |
1996 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The data argue against a role of the angiotensinogen gene M235T polymorphism in the manifestation of diabetic nephropathy or hypertension in diabetic patients.
|
8918618 |
1996 |
rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We evaluated the association among the M235T and T174M variants of the angiotensinogen (AGT) gene, plasma AGT, and hypertension status in a sample of Nigerians.
|
9170394 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To examine whether the angiotensinogen M235T and angiotensin converting enzyme insertion/deletion (I/D) variants are related to the severity of hypertension in patients with established essential hypertension.
|
9170002 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In studies conducted in several different populations, the M235T substitution in the angiotensinogen (AGT) locus has been associated with hypertension.
|
9034402 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that C-18T polymorphism in AGCE1 is a genetic risk factor for essential hypertension in the Japanese and is more tightly and directly associated with hypertension than TT/M235T.
|
9314411 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The haplotype combining the M235T and G-6A polymorphisms appears as the ancestral allele of the human AGT gene and as the one associated with hypertension.
|
9199566 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The odds ratio for hypertension was 3.64 (95% confidence interval 1.56-8.49) for subjects with the C/C genotype of the M235T variant compared with other genotypes of 2.87 (95% confidence interval 1.76-4.68) for those carrying allele C versus those carrying allele T.
|
9218179 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The consistent relationships observed between the M235T variant and the protein product and between plasma level of the protein and hypertension status in different ethnic groups provide some evidence for a biochemical mechanism linking DNA variation in the renin-angiotensin system with the hypertension phenotype.
|
9170394 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We studied the relation between the M235T polymorphism of the angiotensinogen gene and hypertension using office and ambulatory (BP) measurements.
|
9194517 |
1997 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Furthermore, an M235T variant of the angiotensinogen (AGT) gene has been associated with hypertension, an important risk factor for the development and progression of diabetic nephropathy.
|
9049480 |
1997 |
rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The AGT T174M and ACE I/D polymorphisms were not associated with hypertension.
|
9533415 |
1998 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
M235T polymorphism of the angiotensinogen gene and hypertension in Chinese.
|
9794717 |
1998 |
rs4762
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, this study provides no evidence that either allele of M235T or T174M contributes to hypertension in this Chinese population.
|
10024331 |
1999 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association study of G(-6)A, A(-20)C and M235T variants in 111 hypertensives with strong family history and 190 normotensives with no family history showed significant linkage disequilibrium between particular haplotypes, but we could find no association with hypertension.
|
10528248 |
1999 |
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study was undertaken to investigate the relationship of the M235T polymorphism of the AGT gene with left ventricular mass (LVM) and carotid intima-media thickness (IMT) in 175 Chinese patients with hypertension.
|
10342781 |
1999 |