|
rs1078499
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension.
|
27398822 |
2016 |
|
rs11122577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension.
|
27398822 |
2016 |
|
rs5050
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 4 polymorphisms of angiotensinogen (AGT) gene A-20C (rs5050), A-6G (rs5051), C3889T (rs4762), and C4072T (rs699) by polymerase chain reaction-restriction fragment length polymorphism in 652 patients and 780 controls to examine the association of AGT and hypertension in a Northern Han Chinese population.
|
23716723 |
2014 |
|
rs1177506410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotypic distribution of the Met235Thr (AGT) and Glu298Asp (NOS3) polymorphisms demonstrated that both are independent risk factors of hypertension (p=0.02 and p=0.008, respectively).
|
22791701 |
2013 |
|
rs1275805226
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotypic distribution of the Met235Thr (AGT) and Glu298Asp (NOS3) polymorphisms demonstrated that both are independent risk factors of hypertension (p=0.02 and p=0.008, respectively).
|
22791701 |
2013 |
|
rs2067853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six variants, rs2067853 GG [Odds ratio(95% Confidence Interval) = 1.44(1.17-1.78); p = 0.001], rs7079 [1.49(1.20-1.85); p < 0.0001], rs699 G [1.19(1.08-1.13); p < 0.0001], rs3789679 A [1.51(1.14-1.99); p = 0.004], rs2148582 GG [1.31(1.11-1.55); p = 0.002] and rs5051 TC + CC [1.32(1.13-1.60); p = 0.001] conferred risk for HTN (3521 cases versus 1094 controls).
|
23497386 |
2013 |
|
rs2148582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six variants, rs2067853 GG [Odds ratio(95% Confidence Interval) = 1.44(1.17-1.78); p = 0.001], rs7079 [1.49(1.20-1.85); p < 0.0001], rs699 G [1.19(1.08-1.13); p < 0.0001], rs3789679 A [1.51(1.14-1.99); p = 0.004], rs2148582 GG [1.31(1.11-1.55); p = 0.002] and rs5051 TC + CC [1.32(1.13-1.60); p = 0.001] conferred risk for HTN (3521 cases versus 1094 controls).
|
23497386 |
2013 |
|
rs2493132
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of 41 SNPs genotyped, rs3789678 and rs2493132 within AGT, rs4305 within ACE, rs275645 within AGTR1, rs3802230 and rs10086846 within CYP11B2 were shown to associate with hypertension.
|
24015270 |
2013 |
|
rs3789679
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six variants, rs2067853 GG [Odds ratio(95% Confidence Interval) = 1.44(1.17-1.78); p = 0.001], rs7079 [1.49(1.20-1.85); p < 0.0001], rs699 G [1.19(1.08-1.13); p < 0.0001], rs3789679 A [1.51(1.14-1.99); p = 0.004], rs2148582 GG [1.31(1.11-1.55); p = 0.002] and rs5051 TC + CC [1.32(1.13-1.60); p = 0.001] conferred risk for HTN (3521 cases versus 1094 controls).
|
23497386 |
2013 |
|
rs7079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six variants, rs2067853 GG [Odds ratio(95% Confidence Interval) = 1.44(1.17-1.78); p = 0.001], rs7079 [1.49(1.20-1.85); p < 0.0001], rs699 G [1.19(1.08-1.13); p < 0.0001], rs3789679 A [1.51(1.14-1.99); p = 0.004], rs2148582 GG [1.31(1.11-1.55); p = 0.002] and rs5051 TC + CC [1.32(1.13-1.60); p = 0.001] conferred risk for HTN (3521 cases versus 1094 controls).
|
23497386 |
2013 |
|
rs762079672
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the A640G gene variation with the presence and extent of CAD was not only identified in the total sample, but was even stronger in various high risk subpopulations of younger individuals (e.g. with hypertension with or without increased apolipoprotein B plasma levels).
|
10488959 |
1999 |
|
rs2004776
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genome-wide association studies have shown that two A/G polymorphisms (rs2493134 and rs2004776), located at +507 and +1164 in intron I of the human <i>AGT</i> (<i>hAGT</i>) gene, are associated with hypertension.
|
31201268 |
2019 |
|
rs2493134
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genome-wide association studies have shown that two A/G polymorphisms (rs2493134 and rs2004776), located at +507 and +1164 in intron I of the human <i>AGT</i> (<i>hAGT</i>) gene, are associated with hypertension.
|
31201268 |
2019 |
|
rs3889728
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The model for SBP consists of 6 environmental factors (age, BMI, waist circumference, exercise [times per week], parental history of hypertension [either or both]) and 1 SNP (rs7305099); model for DBP consists of 6 environmental factors (weight, drinking, exercise [times per week], TG, parental history of hypertension [either and both]) and 3 SNPs (rs5193, rs7305099, rs3889728).
|
31337952 |
2019 |
|
rs2493134
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension.
|
27398822 |
2016 |
|
rs3789678
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension.
|
27398822 |
2016 |
|
rs7539020
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension.
|
27398822 |
2016 |
|
rs3789678
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In multilocus haplotype analysis, the association between frequencies of the haplotypes and AF risk was showed in AGT gene (rs7539020-rs3789678), compared 'TT' haplotype with the common 'TC' haplotype, adjusted for age, gender, LVEF, LVEDD, LAD and frequency of hypertension and diabetes.
|
25723521 |
2015 |
|
rs3889728
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The RCC risk for AGT_rs3889728 (AG + AA vs. GG) was modified by hypertension (p interaction = 0.039).
|
24978482 |
2015 |
|
rs7539020
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In multilocus haplotype analysis, the association between frequencies of the haplotypes and AF risk was showed in AGT gene (rs7539020-rs3789678), compared 'TT' haplotype with the common 'TC' haplotype, adjusted for age, gender, LVEF, LVEDD, LAD and frequency of hypertension and diabetes.
|
25723521 |
2015 |
|
rs5051
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We genotyped 4 polymorphisms of angiotensinogen (AGT) gene A-20C (rs5050), A-6G (rs5051), C3889T (rs4762), and C4072T (rs699) by polymerase chain reaction-restriction fragment length polymorphism in 652 patients and 780 controls to examine the association of AGT and hypertension in a Northern Han Chinese population.
|
23716723 |
2014 |
|
rs5049
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the A/A genotype at rs5049 was a risk factor for hypertension (P=0.025) in the Melanesian Solomon Islanders; three SNPs for AGT were in linkage disequilibrium.
|
23324949 |
2013 |
|
rs5051
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Six variants, rs2067853 GG [Odds ratio(95% Confidence Interval) = 1.44(1.17-1.78); p = 0.001], rs7079 [1.49(1.20-1.85); p < 0.0001], rs699 G [1.19(1.08-1.13); p < 0.0001], rs3789679 A [1.51(1.14-1.99); p = 0.004], rs2148582 GG [1.31(1.11-1.55); p = 0.002] and rs5051 TC + CC [1.32(1.13-1.60); p = 0.001] conferred risk for HTN (3521 cases versus 1094 controls).
|
23497386 |
2013 |
|
rs2004776
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Variation in AGT (rs2004776) was associated with systolic blood pressure (β: 0.42 mm Hg; SE: 0.09 mm Hg; meta-analysis: P=3.8×10(-6)), as well as diastolic blood pressure (P=5.0×10(-8)) and hypertension (P=3.7×10(-7)).
|
21444836 |
2011 |
|
rs5049
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571).
|
21157371 |
2011 |