Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs768678989
rs768678989
MET
0.710 GeneticVariation UNIPROT A novel germ line juxtamembrane Met mutation in human gastric cancer. 11042681

2000

dbSNP: rs768678989
rs768678989
MET
0.710 GeneticVariation BEFREE Here we report a novel germline missense Met mutation, P1009S, in a patient with primary gastric cancer. 11042681

2000

dbSNP: rs771333219
rs771333219
MET
0.700 GeneticVariation UNIPROT A novel germline mutation in the MET extracellular domain in a Korean patient with the diffuse type of familial gastric cancer. 12920089

2003

dbSNP: rs63749803
rs63749803
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750297
rs63750297
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750623
rs63750623
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750709
rs63750709
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750795
rs63750795
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63750966
rs63750966
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63751047
rs63751047
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs63751400
rs63751400
0.700 GeneticVariation UNIPROT hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. 12132870

2002

dbSNP: rs780759537
rs780759537
0.700 GeneticVariation UNIPROT

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE In conclusion, the results indicated that the PSCA rs2294008 T and rs2976392 A alleles were low-penetrate risk factors for GCa in this study population. 26848528

2017

dbSNP: rs25487
rs25487
0.100 GeneticVariation BEFREE These findings suggest that XRCC1 rs25487 and GSTP1 rs1695 can be considered as a risk factor associated with gastric cancer and might be used as a molecular marker for evaluating the susceptibility of the disease. 26768611

2017

dbSNP: rs25487
rs25487
0.100 GeneticVariation BEFREE Our findings demonstrated that XRCC1 gene rs25487 polymorphism might play a leading role in pronounced susceptibility to gastric cancer in Han Chinese. 26590607

2017

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Genetic Variation of BCL2 (rs2279115), NEIL2 (rs804270), LTA (rs909253), PSCA (rs2294008) and PLCE1 (rs3765524, rs10509670) Genes and Their Correlation to Gastric Cancer Risk Based on Universal Tagged Arrays and Fe3O4 Magnetic Nanoparticles. 26554163

2016

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Based on the statistical evidence, we can draw a conclusion that the rs2294008 polymorphism of PSCA gene is likely to play a role in cancer carcinogenesis, especially in gastric cancer and bladder cancer. 26308216

2016

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Specifically, a significant increased stomach cancer risk was associated with PSCA rs2294008 (CT vs. CC: adjusted OR = 1.37, 95% CI = 1.07-1.74, and CT/TT vs.CC: adjusted OR = 1.30, 95% CI = 1.03-1.63), PSCA rs2976392 (AG vs. GG: adjusted OR = 1.30, 95% CI = 1.02-1.65, and AG/AA vs. GG: adjusted OR = 1.26, 95% CI = 1.00-1.59), or PLCE1 rs2274223 (AG vs. AA: adjusted OR = 1.48, 95% CI = 1.15-1.90, and AG/GG vs. AA: adjusted OR = 1.45, 95% CI = 1.14-1.84), respectively. 25658482

2016

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The PSCA rs2294008 C>T polymorphism may be acting through induction of gastric mucosal atrophy, finally leading to development of gastric ulcer and gastric cancer in PSCA rs2294008 T allele carriers, but not duodenal ulcer. 25582162

2015

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease. 25721731

2015

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE Our findings demonstrated that rs2294008 and rs2976392 polymorphism of PSCA is a risk-conferring factor associated with increased GC susceptibility, especially in East Asians. 24146278

2014

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE We found that the T allele of rs2294008, an intronic variant of the PSCA gene at 8q24 that was previously associated with an increased risk of gastric cancer, was inversely associated with a decreased risk of ESCC (odds ratio = 0.90; 95% confidence interval, 0.81-0.99; P = 0.034). 24654646

2014

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE The variant C allele of the reference SNP rs2294008 in the PSCA gene was associated with a significantly reduced risk of GC (per allele-adjusted odds ratio [aOR], 0.51; 95% confidence interval [CI], 0.33-0.77; P = .002). 24962126

2014

dbSNP: rs2294008
rs2294008
0.100 GeneticVariation BEFREE We analyzed 3 SNPs in the PSCA gene (rs2294008, rs9297976 and rs12155758) which were previously found to be associated with GC risk in Europeans. 24023815

2014

dbSNP: rs25487
rs25487
0.100 GeneticVariation BEFREE Results from the current meta-analysis indicate that XRCC1 Arg399Gln polymorphism may be associated with poor clinical outcomes in GC patients treated with oxaliplatin-based chemotherapy. 24590266

2014