|
rs10914456
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>Conclusion.</i> This study suggests that, <i>Orx<sub>1</sub></i> rs10914456 and rs2271933 can be associated with MDD development.
|
30596528 |
2019 |
|
rs2271933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>Conclusion.</i> This study suggests that, <i>Orx<sub>1</sub></i> rs10914456 and rs2271933 can be associated with MDD development.
|
30596528 |
2019 |
|
rs397507444
|
|
|
0.050 |
GeneticVariation |
BEFREE |
<i>MTHFR</i> A1298C is implicated in irregular homocysteine metabolism and aberrant folate cycles and, through this, it may play a role as either a driver in the development of MDD or as a predictive or diagnostic marker, possibly in combination with C677T.
|
29209581 |
2017 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<i>MTHFR</i> A1298C is implicated in irregular homocysteine metabolism and aberrant folate cycles and, through this, it may play a role as either a driver in the development of MDD or as a predictive or diagnostic marker, possibly in combination with C677T.
|
29209581 |
2017 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
330 adult patients with MDD (DSM-5) and positive for either MTHFR C677T or A1298C polymorphism were enrolled in a trial conducted between August 1, 2014, and April 3, 2015.
|
27035272 |
2016 |
|
rs397507444
|
|
|
0.050 |
GeneticVariation |
BEFREE |
330 adult patients with MDD (DSM-5) and positive for either MTHFR C677T or A1298C polymorphism were enrolled in a trial conducted between August 1, 2014, and April 3, 2015.
|
27035272 |
2016 |
|
rs25531
|
|
|
0.060 |
GeneticVariation |
BEFREE |
49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531.
|
22086748 |
2012 |
|
rs2273816
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Major depression was also associated with rs2273816 but only at the allele level.
|
22960338 |
2012 |
|
rs2032582
|
|
|
0.030 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs1128503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs1045642
|
|
|
0.070 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs2032583
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs2235040
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs2235015
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MDD is associated with the rs2032582 (<i>G2677T</i>) and rs1128503 (<i>C1236T</i>) single-nucleotide polymorphisms (SNPs) of <i>ABCB1</i> but not with rs1045642, rs2032583, rs2235040, and rs2235015.
|
31333472 |
2019 |
|
rs10061623
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs10061623 showed initial association with MDD in females in the allele analysis (p-value: 0.043).
|
23619526 |
2013 |
|
rs6883197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs6883197 and rs259127 were significantly associated with schizophrenia, and rs12514461, rs259127, and rs7343 were associated with major depressive disorder.
|
24988482 |
2014 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
rs4680 in COMT and rs3219151 in GABRA6 showed positive associations with PD and MDD.
|
25974322 |
2015 |
|
rs6983724
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A cis SNP (rs6983724, ∼28 kb downstream of SCL25A37) showed significant association with SCL25A37 expression (P = 1.19 × 10<sup>-9</sup>) and suggestive association with MDD (P = 1.65 × 10<sup>-7</sup>).
|
27643475 |
2016 |
|
rs77554113
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers.
|
30034349 |
2018 |
|
rs2242446
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A functional NET T-182C polymorphism (rs2242446) in the promoter region and a synonymous polymorphisms G1287A in the exon 9 (rs5569) were associated with MDD in different populations.
|
29703117 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs77044609
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders.
|
31123309 |
2019 |
|
rs2522833
|
|
|
0.780 |
GeneticVariation |
BEFREE |
A genome-wide association study implicated the polymorphism rs2522833 in the piccolo (PCLO) gene--involved in monoaminergic neurotransmission--as a risk factor for MDD.
|
22832909 |
2012 |
|
rs7785360
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study of antidepressant response in Koreans.
|
26348319 |
2015 |