rs10486567
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer: statistical evaluation of epistasis.
|
24586834 |
2014 |
rs4242382
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer: statistical evaluation of epistasis.
|
24586834 |
2014 |
rs2645429
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele of rs2645429 was significantly associated with prostate cancer risk in a Japanese familial prostate cancer population.
|
22546838 |
2012 |
rs1447295
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of SNP rs1447295 and microsatellite marker DG8S737 with familial prostate cancer and high grade disease.
|
20639049 |
2010 |
rs1042028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study was conducted to confirm the association of a G638A polymorphism, Arg213His, in SULT1A1 with familial prostate cancer risk in a Japanese population.
|
18368507 |
2008 |
rs117251022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs1374051619
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping of HPC2/ELAC2 variants (S217L, A541T), along with RNASEL variants (R462Q and E541D) was completed in 155 African American sporadic and 88 familial prostate cancer cases, and 296 healthy male controls.
|
18767027 |
2008 |
rs34301344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs755100942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs9282861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study was conducted to confirm the association of a G638A polymorphism, Arg213His, in SULT1A1 with familial prostate cancer risk in a Japanese population.
|
18368507 |
2008 |
rs1114167843
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M.
|
16963262 |
2006 |
rs1799977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found.
|
16963262 |
2006 |
rs35831931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M.
|
16963262 |
2006 |
rs536562413
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found.
|
16963262 |
2006 |
rs63750109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M.
|
16963262 |
2006 |
rs17879961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
I157T was identified in 16% of men with familial prostate cancer (OR = 3.8; P = 0.00002).
|
15087378 |
2004 |
rs137852593
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AR R726L allele does not account for a significant proportion of early-onset and/or familial prostate cancer in the United States.
|
12539229 |
2003 |
rs78105154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An epidemiological study was done in sporadic PCa (n=98) and BPH (n=143) using 1 novel (Ser627Leu) and 2 previously described polymorphisms of the HPC2/ELAC2 gene.
|
12949798 |
2003 |
rs5030739
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A truncating mutation was found in one hereditary prostate cancer (HPC) family, whereas two missense variants, Ser217Leu and Ala541Thr, were reported to be associated with increased PRCA risk in the general population.
|
11507049 |
2001 |
rs3803185
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study provides strong confirmation of the important role of ARLTS1 Cys148Arg variant as a contributor in PCa predisposition and a potential marker for aggressive disease outcome.
|
22028916 |
2011 |
rs3803185
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs627928
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genotyping of HPC2/ELAC2 variants (S217L, A541T), along with RNASEL variants (R462Q and E541D) was completed in 155 African American sporadic and 88 familial prostate cancer cases, and 296 healthy male controls.
|
18767027 |
2008 |
rs74315364
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The RNASEL (encoding ribonuclease L) gene Glu265X mutation has been implicated in familial prostate cancer, and an association between the RNASEL Arg462Gln variant and sporadic and familial prostate cancer, has also been suggested.
|
15981205 |
2005 |
rs74315364
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Cosegregation between the truncating mutation E265X and disease in a hereditary prostate cancer (HPC) family and association between prostate cancer risk and the common missense variant R462Q has been reported.
|
15534086 |
2004 |
rs627928
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To further test for potential associations between genes and increased risk for disease, the three missense polymorphisms (Ile97Leu, Arg462Gln, and Glu541Asp) were genotyped in 438 patients with familial PC and in 510 population-based control subjects.
|
12022038 |
2002 |