|
Hereditary lymphedema and yellow nails
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunohistochemistry was performed on archival sinonasal mucosal samples from 5 patients with YNS and 14 controls with antibodies against podoplanin and CD31, markers of lymphatics.
|
31589812 |
2020 |
|
Erythroplakia of mouth
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Strikingly, we observed that the expression of podoplanin and ABCG2 within a single pre-neoplastic OE lesion significantly correlate with subsequently developing multiple and multifocal carcinomas, thus to some extent demonstrating the concept of field cancerization.
|
31300272 |
2020 |
|
Malignant Head and Neck Neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin and ABCG2 are promising marker of CSCs for head and neck cancer.
|
31300272 |
2020 |
|
Head and Neck Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin and ABCG2 are promising marker of CSCs for head and neck cancer.
|
31300272 |
2020 |
|
Aortic Valve Insufficiency
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We determined podoplanin expression in human aortic valves in four patient groups: control (C, n=7), aortic regurgitation (AR, n=8), aortic regurgitation and fibrosis (AR + f, n=15) and AS (n=49) by immunohistochemistry and quantitative real-time PCR (RT-PCR).
|
30616084 |
2019 |
|
Aortic Valve Stenosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Podoplanin mRNA levels were 1.7-fold higher in the AS group as compared with the control group (P=.05).
|
30616084 |
2019 |
|
Basal Cell Nevus Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Further, podoplanin expression was the highest in the suprabasal layer of NBCCS lesions, followed by the suprabasal layers of OK and OOC lesions.
|
31241560 |
2019 |
|
Malignant neoplasm of skin
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The Prognostic Value of Podoplanin Expression in Nonmelanoma Skin Cancers: Correlation With Lymphatic Vessel Density.
|
31688008 |
2019 |
|
Carcinoma, Basosquamous
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The highest mean value of podoplanin expression (both intratumoral and peritumoral cells) was observed in SCC followed by BSC, then BCC, SK, and control skin in the same sequence.
|
31688008 |
2019 |
|
Diabetic Nephropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin mediates the renoprotective effect of berberine on diabetic kidney disease in mice.
|
31270434 |
2019 |
|
Hyperglycemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Administration of berberine (100, 200 mg/kg every day, ig, for 8 weeks) significantly improved hyperglycemia and the renal function of STZ-induced diabetic mice and restored the expression level of podoplanin in renal glomerulus.
|
31270434 |
2019 |
|
Seborrheic keratosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
This work aimed at studying the immunohistochemical expression of podoplanin in nonmelanoma skin cancers (NMSCs) and seborrheic keratosis (SK) in comparison to normal control skin and to evaluate its possible role in their pathogenesis.
|
31688008 |
2019 |
|
Degenerative polyarthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis.
|
31351471 |
2019 |
|
Pancreatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin (Th17 marker)-expressing lymphocytes were present in the lymphoid follicles of those with follicular pancreatitis, whereas these were absent in normal lymph nodes and in lymphoid follicles of those with IgG4-related autoimmune pancreatitis (AIP).
|
30515871 |
2019 |
|
Periodontal Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Podoplanin expression is highly associated with an increased inflammatory infiltration suggesting that PDPN might play an additional role in periodontal disease, other than solely as a lymphangiogenesis marker.
|
30656679 |
2019 |
|
Pterygium
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Primary grade 2 pterygium (n=20) and normal conjunctiva (n=20) biopsies were obtained during surgery after written informed consent. mRNA expression for CD31, podoplanin, and VEGF (isoforms VEGF-A and VEGF-165) were determined by qRT-PCR.
|
30821336 |
2019 |
|
Skin Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Podoplanin plays an evident role in the development and progression of both benign and malignant skin neoplasms and may serve as a potential predictor of their clinical course and prognosis.
|
31688008 |
2019 |
|
Vascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
They did not differ in anthropometric or histomorphometric parameters [mesothelial coverage, submesothelial fibrosis, blood, and lymphatic vascularization, leukocyte, macrophage and activated fibroblast counts, epithelial-mesenchymal transition (EMT), podoplanin positivity and vasculopathy].
|
31001140 |
2019 |
|
Virus Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection.
|
31309159 |
2019 |
|
Lip Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Podoplanin and CD44v6 were strongly expressed by tumor cells and podoplanin immunoexpression can help to determine lip cancer patients with lower risk for disease recurrence.
|
30770986 |
2019 |
|
Cancer of Lip
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Podoplanin and CD44v6 were strongly expressed by tumor cells and podoplanin immunoexpression can help to determine lip cancer patients with lower risk for disease recurrence.
|
30770986 |
2019 |
|
Malignant neoplasm of nasopharynx
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Endogenous PDPN expression in C8161 cells and nasopharyngeal cancer cell line CNE-2 was detected using western blot and flow cytometry.
|
31208371 |
2019 |
|
Acute myocardial infarction
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction.
|
31287805 |
2019 |
|
Acute intermittent porphyria
|
0.010 |
Biomarker
|
disease |
BEFREE |
Podoplanin (Th17 marker)-expressing lymphocytes were present in the lymphoid follicles of those with follicular pancreatitis, whereas these were absent in normal lymph nodes and in lymphoid follicles of those with IgG4-related autoimmune pancreatitis (AIP).
|
30515871 |
2019 |
|
Carcinoma, Signet Ring Cell
|
0.010 |
Biomarker
|
disease |
BEFREE |
An observational retrospective study on 50 cases of SRC in stage II and III has been performed with the addition of histochemical (Alcian Blue, DDD-Fast Blue B, Mercury Orange) and immunohistochemical (cytocheratin, CD3, CD4, CD8, CD10, CD56, CD68, perforin, granzyme B, podoplanin, collagen type IV) investigations for each case.
|
30064231 |
2019 |