|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
A total of 177 patients with RA and 150 healthy volunteers participated in this study, which measured lipid hydroperoxides, advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), carbonyl protein, total radical-trapping antioxidant parameter (TRAP), uric acid (UA), and C-reactive protein (CRP).
|
29644482 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Low hemoglobin is a DAS28-CRP-independent predictor of radiographic joint damage progression in MTX-treated patients with early RA.
|
28950430 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Circulating adiponectin level was not associated with RA activity based on DAS28 and C-reactive protein (CRP) levels.
|
28205390 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Stratification analysis found a significantly increased risk for RA associated with the APOM rs805297 TT genotype among male patients, C-reactive protein (CRP)-positive patients, anticitrullinated protein/peptide antibodies (ACPA) - positive patients, rheumatoid factor (RF) - positive patients, patients with higher levels of the erythrocyte sedimentation rate (ESR), patients with higher DAS28 score and patients with higher functional class compared to the APOM rs805297 GG genotype.
|
23660425 |
2014 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We further investigated the relationships among the genotypes of each polymorphism and C-reactive protein or rheumatoid factor levels in RA patients.
|
15565336 |
2005 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Additionally, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), disease activity score (DAS), visual analog scala (VAS), HLA genotype and radiographic information were determined in patients with RA.
|
18418600 |
2008 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
To compare the multi-biomarker disease activity (MBDA) score with the DAS28-CRP and CRP for predicting risk of radiographic progression in patients with rheumatoid arthritis.
|
30777458 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Participants in a prospective RA cohort who experienced a decrease or an increase of ≥10 mg/liter in the C-reactive protein (CRP) level at 2 consecutive time points 1 year apart (CRP decrease group and CRP increase group, respectively) were included in this study.
|
29676517 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The RA group had higher CRP (P = 0.006), were more likely to receive glucocorticoids (P<0.001), and experienced worse fatigue (P = 0.050).
|
31170172 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Multivariate regression analysis demonstrated significant correlations between GLSs and RA duration (p = 0.02), and GLSs and DAS28-CRP (p = 0.041).
|
31843000 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The increase of blood platelet, and CRP levels and decrease of blood albumin are probable risk factors for PN in RA patients.
|
30911944 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Periodontal local treatment only affects clinical periodontal status, and it does not alter circulating levels of IL-6, tumor necrosis factor-alpha or C-reactive protein which are associated with RA.
|
29341486 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The objective of the present study was to explore the associations between calprotectin, S100A12, IL-6, VEGF, erythrocyte sedimentation rate, C-reactive protein and a comprehensive US assessment in patients with rheumatoid arthritis (RA) starting biologic disease-modifying anti-rheumatic drug (bDMARD) treatment.
|
28081709 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Moreover, this polymorphism was significantly associated with mean concentration of C-reactive protein in RA patients.
|
21645266 |
2011 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
We have shown that serum levels of reactive oxygen metabolites (ROM) were associated with C-reactive protein (CRP) and disease activity score based on the examination of 28 joints (DAS28) in patients with rheumatoid arthritis (RA); however, their clinical significance as biomarkers has not been elucidated.
|
27858176 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Longitudinal association between CRP and BP was examined using a repeated-measures linear mixed-effects model in RA outpatients with significant change in inflammation at two consecutive time points.
|
29855349 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we evaluated the frequency and potential impact of IL-10 promoter polymorphisms on susceptibility to and severity of RA in Polish in - patients with a high disease activity (mean DAS 28 C-reactive protein 5.25).
|
20477882 |
2010 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Further, JNK levels were inversely correlated with C-reactive protein levels in RA patients.
|
22183962 |
2012 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Forty consecutive patients who experienced TdP (TdP cohort) were consecutively enrolled and circulating levels of C-reactive protein (CRP) and proinflammatory cytokines (interleukin-6 (IL-6), tumour necrosis factor alpha (TNFα), interleukin-1 (IL-1)) were compared with patients with active rheumatoid arthritis (RA), comorbidity or healthy controls.
|
28490617 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In conclusion, IL-1β, IL-17A, CRP and biologics history would serve as potential markers for clinical response to ETN in RA patients.
|
31463666 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Most patients with RA had low to moderate disease activity [28-joint count Disease Activity Score-C-reactive protein median 3.16, interquartile range (IQR) 2.03-4.05], and 49% were receiving anti-tumor necrosis factor agents.
|
29657146 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
CRP was measured preoperatively as the disease activity marker for rheumatoid arthritis.
|
28853601 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
C-reactive protein was also used to measure disease activity in RA patients.
|
28831245 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Disease Activity Score in 28 joints (DAS28) is commonly used to evaluate disease activity of rheumatoid arthritis (RA) and is a guide to treatment decision.The aim of this study was to evaluate the impact of lower reporting limit for C-reactive protein (CRP), with respect to intraindividual biological variability, on the calculation of DAS28 and subsequent patient classification.This study consists of 2 sections: a theoretical consideration discussing the performance of CRP in calculating DAS28 taking intraindividual biological variation and lower reporting limit for CRP into account and a cross-sectional study of RA patients applying our theoretical results.
|
28072726 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
To investigate serum interleukin (IL)- 35 levels in patients with rheumatoid arthritis (RA) and to describe the association between serum IL-35 levels and clinical parameters: erythrocyte sedimentation rate (ESR), C reactive protein (CRP), global health on Visual Analog Scale, Disease Activity Score in 28 joints based on ESR (DAS28-ESR), rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (ACPAs).
|
30659089 |
2019 |