|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Levels of circulating C-reactive protein are reported to decrease in RA patients receiving long-acting antirheumatic drugs, which would be consistent with the interpretation that immature monocyte-derived macrophages are major producers of IL-6 in these patients.
|
2786697 |
1989 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Longitudinal data on 36 RA patients demonstrated a significant positive correlation between changes in CRP and changes in anti-Proteus antibody titres (r = 0.52, P less than 0.001).
|
1555039 |
1992 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
CTD_human |
Multiple intra-articular treatment of rheumatoid arthritis: a randomized prospective study comparing rifamycin SV with pefloxacin.
|
1568518 |
1992 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Multiple logistic regression analysis demonstrated that ESR, CRP and genetic markers were the most relevant independent variables and when combined could indicate the outcome in early RA.
|
7633794 |
1995 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Moreover, SF thrombin concentrations of patients with RA correlated significantly with erythrocyte sedimentation rates (rs = 0.751, p < 0.01) and serum C-reactive protein concentrations (rs = 0.531, p < 0.05).
|
8877916 |
1996 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
These results provide histochemical evidence that rheumatoid synoviocytes strongly express NK1 gene, and the positive relation of the signal intensity of NK1 mRNA with CRP and radiographic severity suggests that the facilitation of NK1 gene expression in rheumatoid synovium relate the disease progression of RA.
|
9572640 |
1998 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Collagenase 3 mRNA was detected in synovial membrane specimens of 21 of 36 RA patients (58%) and correlated with an increase in erythrocyte sedimentation rate (P<0.05) and C-reactive protein levels (P<0.005).
|
10403281 |
1999 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Significant correlations were noted between increasing DI and duration of RA and concentration of C reactive protein.
|
10531075 |
1999 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In RA, detection of those antibodies was significantly associated with disease activity indices such as serum C-reactive protein (CRP) levels, erythrocyte sedimentation rate, blood platelet counts, and serum IL-6 concentration.
|
10880057 |
2000 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Elevated CRP (> or = 15 mg/l) increased the probability of erosive RA in DRB1*04 or DRB1*01 positive patients from 64.0% (in patients with CRP < 15 mg/l) to 83.9%, and in DRB1*04 and DRB1*01 negative patients from 18.8% to 70.1%.
|
10990219 |
2000 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
These findings, together with the positive association between MBL variant alleles and the increased serum levels of IgM RF and CRP, point at the MBL gene as a relevant locus in the pathophysiology of RA.
|
11361219 |
2001 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
SAA and C reactive protein (CRP) concentrations together with SAA1 genotypes were determined in 316 Japanese patients with RA.
|
11156544 |
2001 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
An increased IL-1 beta 2 carriage is associated with active rheumatoid disease as indicated by a higher CRP (P < 0.001), ESR (P < 0.001) and pain score (P = 0.001) and a higher BMD at the lumbar spine (P = 0.007), lower vit-D3 and.
|
11930657 |
2002 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
There was no significant difference in age at onset, severity, functional class (> or = 3), physician global assessment, ESR, CRP or RF titer in patients with RA according to the CTLA-4 polymorphisms.
|
12455815 |
2002 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
We investigated the serum enzyme activity and concentration of PON1 and their relationship with serum lipids, high-density lipoprotein (HDL) parameters, and acute phase reactants of serum amyloid A (SAA) and C-reactive protein (CRP) in patients with RA.
|
12697270 |
2003 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
CRP in RA patients correlated with DPD and inversely with PTH.
|
12846052 |
2003 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Additionally, there were significant correlations between the amount of GRalpha mRNA and inflammatory indices such as erythrocyte sedimentation rate (p < 0.001) and C-reactive protein (p < 0.05) in the RA patients.
|
14994389 |
2004 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We further investigated the relationships between the genotypes of each single nucleotide polymorphisms (SNPs) and C-reactive protein (CRP) or rheumatoid factor (RF) levels in RA patients.
|
15325803 |
2004 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We further investigated the relationships among these variations to C-reactive protein (CRP) and rheumatoid factor (RF) levels in RA patients.
|
14985107 |
2004 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We further investigated the relationships among the genotypes of each polymorphism and C-reactive protein or rheumatoid factor levels in RA patients.
|
15565336 |
2005 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
LHGDN |
Serum C-reactive protein in elderly men and women: association with mortality, morbidity and various biochemical values.
|
15859024 |
2005 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
No significant relationships between expression of tristetraprolin, TIA-1 or HuR genes and TNF-alpha gene expression serum CRP levels in samples from RA patients were observed.
|
16820934 |
2006 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Interleukin (IL)-10, growth hormone (GH), IGF, IGF binding protein (IGFBP)-3 and matrix metalloproteinase (MMP) were measured by ELISA and zymography in 30 age range-matched normal subjects (control), 36 patients with acute phase of rheumatoid arthritis (RA) with positive rheumatoid factor (RF) and C-reactive protein (CRP), and in 43 patients with RHD with negative RF and CRP.
|
16406300 |
2006 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The number of circulating mDCs in RA PB was significantly inversely correlated to C-reactive protein (P = 0.021).
|
16507115 |
2006 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Synovial fluid levels of TN-C in RA did not correlate with C-reactive protein levels.
|
17262825 |
2007 |