|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Quantification of circulating lncRNAs; MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), MIAT (myocardial infarction associated transcript), and ANRIL (antisense non-coding RNA in the INK4 locus) was done by Real-time qRT-PCR.
|
30665334 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
MIAT originally has been considered as an lncRNA to be associated with a susceptibility to myocardial infarction.
|
29345338 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Dysregulation of the lncRNA known as myocardial infarction-associated transcript (MIAT) has been associated with myocardial infarction.
|
26951817 |
2016 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
The long noncoding RNA myocardial infarction associated transcript (MIAT) is involved in a number of diseases, including myocardial infarction and diabetic retinopathy.
|
29914974 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
We discovered targeting MIAT remarkably enhanced H9c2 cell viability, decreased H/R-induced cell apoptosis and LDH leakage and significantly decreased I/R-induced myocardial infarct size, reduced myocardial apoptosis and enhanced the heart function.
|
30971184 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Myocardial infarction associated transcript (MIAT) is identified as lncRNAs, which is involved in various diseases, pathological and physiological processes, such as myocardial infarction, diabetic retinopathy, paranoid schizophrenia, microvascular dysfunction and formation of nuclear bodies, and neurogenic commitment.
|
26707210 |
2016 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Myocardial infarction associated transcript (MIAT), which was recently found to demonstrate aberrant expression in various diseases, such as myocardial infarction, schizophrenia, ischemic stroke, diabetic complications, age-related cataract and cancers, is a novel disease-related lncRNA.
|
29534728 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Patients with ST-segment-elevation MI had lower levels of ANRIL (P<0.001), KCNQ1OT1 (P<0.001), myocardial infarction-associated transcript (P<0.001), and metastasis-associated lung adenocarcinoma transcript 1 (P=0.005) when compared with patients with non-ST-segment-elevation MI.
|
25035150 |
2014 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI.
|
17066261 |
2006 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
These findings also promise that normalization of MIAT level may prove to be a therapeutic option for the treatment of MI-induced cardiac fibrosis and the associated cardiac dysfunction.
|
28198439 |
2017 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The long noncoding RNA myocardial infarction associated transcript (MIAT) has been shown to be a risk allele for myocardial infarction in a previous study.
|
31661125 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
MIAT, originally isolated as a candidate gene for myocardial infarction, encodes lncRNA (termed MIAT).
|
27527866 |
2016 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
We thus infer that differential expression of MIAT and SNORD114-10 could play an important role during OC metastasis.
|
29387224 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Overall, our findings suggest that MIAT expression is associated with NSCLC and may be one of the critical targets in progression and metastasis in NSCLC.
|
29228680 |
2017 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The above results suggested that MIAT could promote the cell proliferation and the metastasis of Wilms' tumor by upregulating DGCR8, which indicated that MIAT might be a potential target for the diagnosis and therapy of Wilms' tumor.
|
31841180 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The myocardial infarction associated transcript (MIAT), a long non-coding RNA (lncRNA), was originally identified as a candidate gene for myocardial infarction, and was recently shown to participate in the progression of cancer and the process of metastasis.
|
28843520 |
2017 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
MIAT knockdown inhibited GC growth and metastasis both in vitro and in vivo.
|
29540201 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Further, we demonstrated that MIAT acted as a competing endogenous RNA for miR-132, antagonized its functions, and resulted in the de-repression of its target gene Derlin-1, which acted as an oncogene in promoting growth and metastasis of CRC cells.
|
29686537 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Taken together, our results suggest that the interaction of MIAT and miR-133 play a role in the proliferation and metastasis of pancreatic carcinoma.
|
29772434 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
And MIAT overexpression associated with TNM stage and lymphnode metastasis.
|
29100300 |
2017 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
LncRNA MIAT expression was associated with tumor size, lymph node metastasis, distant metastasis and TNM stage.
|
29487526 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Long noncoding RNA MIAT promotes the growth and metastasis of non-small cell lung cancer by upregulating TDP43.
|
31081093 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Functional assays showed that knockdown of MIAT inhibited renal cancer cell proliferation and metastasis in vitro and in vivo.
|
30041179 |
2018 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In addition, knockdown of MIAT suppressed the proliferation, migration and invasion of GC cells in vitro.
|
29039602 |
2017 |
|
Tumor Cell Invasion
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Upregulation of MIAT is related to the proliferation and invasion of HCC, and downregulating MIAT expression inhibited HCC cell proliferation and invasion.
|
29097358 |
2018 |