|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Quantification of circulating lncRNAs; MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), MIAT (myocardial infarction associated transcript), and ANRIL (antisense non-coding RNA in the INK4 locus) was done by Real-time qRT-PCR.
|
30665334 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
We discovered targeting MIAT remarkably enhanced H9c2 cell viability, decreased H/R-induced cell apoptosis and LDH leakage and significantly decreased I/R-induced myocardial infarct size, reduced myocardial apoptosis and enhanced the heart function.
|
30971184 |
2019 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The long noncoding RNA myocardial infarction associated transcript (MIAT) has been shown to be a risk allele for myocardial infarction in a previous study.
|
31661125 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
MIAT originally has been considered as an lncRNA to be associated with a susceptibility to myocardial infarction.
|
29345338 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
The long noncoding RNA myocardial infarction associated transcript (MIAT) is involved in a number of diseases, including myocardial infarction and diabetic retinopathy.
|
29914974 |
2018 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Myocardial infarction associated transcript (MIAT), which was recently found to demonstrate aberrant expression in various diseases, such as myocardial infarction, schizophrenia, ischemic stroke, diabetic complications, age-related cataract and cancers, is a novel disease-related lncRNA.
|
29534728 |
2018 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
These findings also promise that normalization of MIAT level may prove to be a therapeutic option for the treatment of MI-induced cardiac fibrosis and the associated cardiac dysfunction.
|
28198439 |
2017 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Dysregulation of the lncRNA known as myocardial infarction-associated transcript (MIAT) has been associated with myocardial infarction.
|
26951817 |
2016 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Myocardial infarction associated transcript (MIAT) is identified as lncRNAs, which is involved in various diseases, pathological and physiological processes, such as myocardial infarction, diabetic retinopathy, paranoid schizophrenia, microvascular dysfunction and formation of nuclear bodies, and neurogenic commitment.
|
26707210 |
2016 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
MIAT, originally isolated as a candidate gene for myocardial infarction, encodes lncRNA (termed MIAT).
|
27527866 |
2016 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Patients with ST-segment-elevation MI had lower levels of ANRIL (P<0.001), KCNQ1OT1 (P<0.001), myocardial infarction-associated transcript (P<0.001), and metastasis-associated lung adenocarcinoma transcript 1 (P=0.005) when compared with patients with non-ST-segment-elevation MI.
|
25035150 |
2014 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI.
|
17066261 |
2006 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
CTD_human |
These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI.
|
17066261 |
2006 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI.
|
17066261 |
2006 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
LHGDN |
These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI.
|
17066261 |
2006 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The above results suggested that MIAT could promote the cell proliferation and the metastasis of Wilms' tumor by upregulating DGCR8, which indicated that MIAT might be a potential target for the diagnosis and therapy of Wilms' tumor.
|
31841180 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Long noncoding RNA MIAT promotes the growth and metastasis of non-small cell lung cancer by upregulating TDP43.
|
31081093 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Downregulation of the expression of the lncRNA MIAT inhibits melanoma migration and invasion through the PI3K/AKT signaling pathway.
|
30614798 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Cell proliferation, invasion and cycle assay were conducted to study the function of MIAT and LASP1 in PTC.
|
31372094 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Meanwhile, the cell migration and cell invasion were obviously remarkedly inhibited after MIAT knock-down in vitro.
|
31298331 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
MIAT was suppressed and upregulated in TSCC cells, and then cell invasion and epithelial-mesenchymal transition (EMT) markers were analyzed.
|
31166624 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Functional assays showed that knockdown of MIAT in PTC cells significantly inhibited cell proliferation, colony formation, migration and invasion in vitro, as well as impaired tumor growth in vivo.
|
31404776 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
We thus infer that differential expression of MIAT and SNORD114-10 could play an important role during OC metastasis.
|
29387224 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
MIAT knockdown inhibited GC growth and metastasis both in vitro and in vivo.
|
29540201 |
2018 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Further, we demonstrated that MIAT acted as a competing endogenous RNA for miR-132, antagonized its functions, and resulted in the de-repression of its target gene Derlin-1, which acted as an oncogene in promoting growth and metastasis of CRC cells.
|
29686537 |
2018 |