SMOX, spermine oxidase, 54498

N. diseases: 91; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0740391
Disease: Middle Cerebral Artery Occlusion
Middle Cerebral Artery Occlusion
0.310 Biomarker disease CTD_human In this study, we found that Smox expression was increased in a rat middle cerebral artery occlusion (MCAO) model and in cultured primary neurons after oxygen-glucose deprivation and reoxygenation (OGD/R). 30576531 2019
CUI: C0740391
Disease: Middle Cerebral Artery Occlusion
Middle Cerebral Artery Occlusion
0.310 AlteredExpression disease BEFREE In this study, we found that Smox expression was increased in a rat middle cerebral artery occlusion (MCAO) model and in cultured primary neurons after oxygen-glucose deprivation and reoxygenation (OGD/R). 30576531 2019
CUI: C0238281
Disease: Middle Cerebral Artery Syndrome
Middle Cerebral Artery Syndrome
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
CUI: C0740376
Disease: Middle Cerebral Artery Thrombosis
Middle Cerebral Artery Thrombosis
0.300 Biomarker disease CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.300 Biomarker disease CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
CUI: C0751845
Disease: Middle Cerebral Artery Embolus
Middle Cerebral Artery Embolus
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
Left Middle Cerebral Artery Infarction
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
Embolic Infarction, Middle Cerebral Artery
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
Thrombotic Infarction, Middle Cerebral Artery
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
Right Middle Cerebral Artery Infarction
0.300 Biomarker phenotype CTD_human Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. 30576531 2019
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.300 Biomarker group PSYGENET Overall, each gene was associated with at least one main outcome: anxiety (SAT1, SMS), mood disorders (SAT1, SMOX), and suicide attempts (SAT1, OATL1). 21152090 2010
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.300 Biomarker group CTD_human After the onset of stroke, an increase in AcPAO first occurred, followed by increased levels of SMO and finally acrolein. 16269634 2005
CUI: C0751956
Disease: Acute Cerebrovascular Accidents
Acute Cerebrovascular Accidents
0.300 Biomarker disease CTD_human Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke. 16269634 2005
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.300 GeneticVariation disease UNIPROT
CUI: C0005890
Disease: Body Height
Body Height
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 Biomarker disease BEFREE <i>Pseudomonas aeruginosa</i> is an opportunistic pathogen found ubiquitously in the environment and commonly associated with airway infection in patients with cystic fibrosis.<i>P. aeruginosa</i> strain PAO1 is one of the most commonly used laboratory-adapted research strains and is a standard laboratory-adapted strain in multiple laboratories and strain banks worldwide. 30530517 2019
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 Biomarker disease BEFREE Twenty-four hour biofilms formed by the P. aeruginosa strain PAO1 and cystic fibrosis (CF) isolates were tested for susceptibility to oxyclozanide and tobramycin killing using BacTiter-Glo™ and cfu. 30624737 2019
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Red cell distribution width determination
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Finding of Mean Corpuscular Hemoglobin
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
RDW - Red blood cell distribution width result
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 Biomarker disease BEFREE While a reduction in cell growth was observed after 8 h of CORM application, either no effect or even a slight increase in cell densities and the amount of biofilm was observed after 24 h. This variation could be partly explained by differences in bacterial virulence traits: while CF isolates showed attenuated <i>in vivo</i> virulence and growth compared to strain PAO1, they formed much more biofilm, which could have potentially protected them from the CORM. 29472912 2018
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 GeneticVariation disease BEFREE By exploiting this unstable phenotype, we isolated 34 spontaneous nonmucoid variants arising from the mucoid strain PDO300, a PAO1 derivative containing the <i>mucA22</i> allele commonly found in mucoid CF isolates. 29784885 2018
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 Biomarker disease BEFREE In the present study, we evaluate the volatile metabolites produced by P. aeruginosa (PAO1)-infected, RSV-infected, co-infected, or uninfected CF bronchial epithelial (CFBE) cells, in vitro. 29735804 2018
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.100 Biomarker disease BEFREE In the present work, P. aeruginosa strain PAO1, and four multidrug resistant (MDR) isolates from chronically infected CF individuals, were grown as 48-hour biofilms in a static biofilm slide chamber model. 30283025 2018