|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
|
31015462 |
2019 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.
|
30604766 |
2019 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
|
31015462 |
2019 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
|
28452372 |
2017 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
|
28452372 |
2017 |
|
Lipoprotein (a) measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.
|
28512139 |
2017 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.
|
27588450 |
2016 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
|
Creatinine measurement, serum (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic loci influencing kidney function and chronic kidney disease.
|
20383145 |
2010 |
|
Finding of creatinine level
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genetic loci influencing kidney function and chronic kidney disease.
|
20383145 |
2010 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to evaluate whether genetic variations in the SLC22A1, SLC22A2, and SLC47A1 genes could be associated with an altered response to metformin in patients with type 2 diabetes mellitus.
|
31012983 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.
|
27609360 |
2016 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
In this study, we examined the role of OCT2-T201M (602 C>T) variant in insulin resistance in patients with type 2 diabetes (T2D) who were treated with metformin.
|
25662675 |
2015 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
As well as gender, the glucose-lowering efficiency of metformin can be enhanced by SLC22A2 808G > T variants through the delay of its transportation and CLr in Chinese type 2 diabetes populations.
|
25573751 |
2015 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate possible associations of the variants in genes encoding organic cationic transporters-solute carrier family 22, members A1, A2 (SLC22A1, SLC22A2) and solute carrier family 47, member A1 (SLC47A1) with response to metformin in type 2 diabetes.
|
22882994 |
2013 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
The SLC22A2 single nucleotide polymorphism (SNP) 808G/T was genotyped in 400 T2DM patients, including a metformin-treated group (n=200) and a non-metformin-treated group (n=200).
|
20139901 |
2010 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Exemplarily, gene-specific analyses of DNA methylation, mRNA and protein expression demonstrate lack of expression of the clinically important drug transporter OCT2 (encoded by SLC22A2) in cell lines due to hypermethylation compared to tumors or metastases.
|
27435027 |
2016 |
|
Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
We conclude that the expression pattern of OCT2, SSX2-4, and SAGE1 supports the origin of SS from spermatogonia and provides new evidence for heterogeneity of this tumour, potentially linked either to the cellular origin of SS or to partial differentiation during tumour progression, including a hitherto unknown OCT2-positive variant of the tumour likely derived from A(dark) spermatogonia.
|
21706474 |
2011 |