SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031039
Disease: Pericardial effusion
Pericardial effusion 		0.100 Biomarker disease HPO
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		0.100 Biomarker group HPO
CUI: C0034735
Disease: Raynaud Phenomenon
Raynaud Phenomenon 		0.100 Biomarker disease HPO
CUI: C0036572
Disease: Seizures
Seizures 		0.100 Biomarker phenotype HPO
CUI: C0042963
Disease: Vomiting
Vomiting 		0.100 Biomarker phenotype HPO
CUI: C0149745
Disease: Oral Ulcer
Oral Ulcer 		0.100 Biomarker disease HPO
CUI: C0151480
Disease: Anti-nuclear factor positive
Anti-nuclear factor positive 		0.100 Biomarker phenotype HPO
CUI: C0151632
Disease: ESR raised
ESR raised 		0.100 Biomarker phenotype HPO
CUI: C0151786
Disease: Muscle Weakness
Muscle Weakness 		0.100 Biomarker phenotype HPO
CUI: C0221021
Disease: Microangiopathic hemolytic anemia
Microangiopathic hemolytic anemia 		0.100 Biomarker disease HPO
CUI: C0234428
Disease: Disturbance of consciousness
Disturbance of consciousness 		0.100 Biomarker phenotype HPO
CUI: C0277942
Disease: Butterfly rash
Butterfly rash 		0.100 Biomarker phenotype HPO
CUI: C0311370
Disease: Lupus anticoagulant disorder
Lupus anticoagulant disorder 		0.100 Biomarker disease HPO
CUI: C0426396
Disease: Urine looks dark
Urine looks dark 		0.100 Biomarker phenotype HPO
CUI: C0497156
Disease: Lymphadenopathy
Lymphadenopathy 		0.100 Biomarker phenotype HPO
CUI: C1142517
Disease: Lupus anticoagulant measurement
Lupus anticoagulant measurement 		0.100 Biomarker phenotype HPO
CUI: C1837512
Disease: Decreased serum complement C3
Decreased serum complement C3 		0.100 Biomarker phenotype HPO
CUI: C1858981
Disease: Antineutrophil antibody positivity
Antineutrophil antibody positivity 		0.100 Biomarker phenotype HPO
CUI: C4019436
Disease: Antiphospholipid antibody positivity
Antiphospholipid antibody positivity 		0.100 Biomarker phenotype HPO
CUI: C4023588
Disease: Abnormality of the gastrointestinal tract
Abnormality of the gastrointestinal tract 		0.100 Biomarker phenotype HPO
CUI: C4073169
Disease: Decreased serum complement C4
Decreased serum complement C4 		0.100 Biomarker phenotype HPO
CUI: C4321325
Disease: Lupus anticoagulant -- finding
Lupus anticoagulant -- finding 		0.100 Biomarker phenotype HPO
CUI: C4477095
Disease: Increased lactate dehydrogenase activity
Increased lactate dehydrogenase activity 		0.100 Biomarker phenotype HPO
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.100 Biomarker group BEFREE We have found that markedly elevated expression of this protein, which henceforth is referred to as secreted phosphoprotein I (Sppl) closely correlates with neoplastic transformation of a variety of cell types and that patients with advanced stage metastatic cancers have elevated levels of Sppl in their blood. 2686530 1990
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 AlteredExpression group BEFREE Moreover, Sppl expression is induced in mouse epidermal cells in vitro and mouse epidermis in vivo with the tumor promoter TPA (Craig et al, J. Biol.Chem.264: 9682-9689, 1989). 2686530 1990