Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.320 Biomarker disease BEFREE Three candidate genes (HOMER1, SLC6A4 and TEF) were chosen for resequencing analysis and association studies as they were reported to be involved in the etiology of MDD and SA. 27964944 2017
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.320 Biomarker disease PSYGENET Cry1 and Tef gene polymorphisms are associated with major depressive disorder in the Chinese population. 24581835 2014
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.320 GeneticVariation disease BEFREE Cry1 and Tef gene polymorphisms are associated with major depressive disorder in the Chinese population. 24581835 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.310 Biomarker disease PSYGENET Cry1 and Tef gene polymorphisms are associated with major depressive disorder in the Chinese population. 24581835 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.310 GeneticVariation disease BEFREE Cry1 and Tef gene polymorphisms are associated with major depressive disorder in the Chinese population. 24581835 2014
CUI: C0013595
Disease: Eczema
Eczema 		0.100 GeneticVariation disease GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 29942086 2018
CUI: C0042900
Disease: Vitiligo
Vitiligo 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants. 27723757 2016
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.100 GeneticVariation disease GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 GeneticVariation disease BEFREE In a cohort of 396 infants with esophageal atresia, 20 (5%) had RAA, with 18 having EA with a distal TEF and 2 with pure EA. 30224238 2019
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 Biomarker disease BEFREE A male infant with oesophageal atresia and distal tracheo-oesophageal fistula (TEF type C) underwent right thoracotomy and transpleural repair of TEF on day 4 of life. 30413439 2018
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 Biomarker disease BEFREE Esophageal atresia and tracheoesophageal fistula (EA/TEF) are relatively common malformations in newborns, but the etiology of EA/TEF remains unknown. 29621589 2018
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 Biomarker disease BEFREE This retrospective review of 66 patients with postoperative recurrent and acquired TEF following esophageal atresia repair is the largest such series to date and provides a new categorization for postoperative TEF that helps clarify the diagnostic and therapeutic challenges for management. 27616617 2017
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 Biomarker disease BEFREE Esophageal atresia (EA) is a congenital defect of the esophagus involving the interruption of the esophagus with or without connection to the trachea (tracheoesophageal fistula [TEF]). 24460849 2015
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 GeneticVariation disease BEFREE Second study on the recurrence risk of isolated esophageal atresia with or without trachea-esophageal fistula among first-degree relatives: no evidence for increased risk of recurrence of EA/TEF or for malformations of the VATER/VACTERL association spectrum. 24307608 2013
CUI: C0014850
Disease: Esophageal Atresia
Esophageal Atresia 		0.070 GeneticVariation disease BEFREE Shared clinical features in this group of patients include microcephaly, prenatal onset growth restriction, heart defects, tracheoesophageal fistula, and esophageal atresia (TEF/EA), skeletal anomalies, and moderate to severe global developmental delay. 21271665 2011
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality 		0.050 Biomarker group BEFREE Esophageal atresia and tracheoesophageal fistula (EA/TEF) are relatively common malformations in newborns, but the etiology of EA/TEF remains unknown. 29621589 2018
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality 		0.050 Biomarker group BEFREE The frequency of each component was: vertebral defects (V), 77 %; anal atresia (A), 62 %; tracheo-esophageal fistula/esophageal atresia (TEF/EA), 58 %; renal anomalies (R), 58 %; limb abnormalities (L), 50 %, and cardiac malformations (C), 42 %. 25008186 2015
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality 		0.050 Biomarker group BEFREE The presence of EA/TEF and malformations of the VATER/VACTERL association spectrum in relatives was systematically assessed. 24307608 2013
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality 		0.050 Biomarker group BEFREE These findings indicate that intestinal malrotation is more common in infants with EA/TEF than is generally perceived, and that intestinal malrotation in an infant with EA/TEF is associated with a higher burden of additional congenital anomalies, suggesting that this group of infants may have more pervasive developmental deficits and poorer prognosis than has previously been recognized. 10471893 1999
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality 		0.050 Biomarker group BEFREE Esophageal atresia with or without tracheoesophageal fistula (EA +/- TEF) usually occurs sporadically either as an isolated malformation or in conjunction with other congenital anomalies. 6714984 1984
CUI: C1861028
Disease: Esophageal atresia with or without tracheoesophageal fistula
Esophageal atresia with or without tracheoesophageal fistula 		0.040 GeneticVariation disease BEFREE Esophageal atresia with or without tracheoesophageal fistula (EA with or without TEF) is one of the neonatal surgical emergencies requiring surgical intervention in the early neonatal period, influencing the developmental outcome in the operated children. 30597492 2019
CUI: C1861028
Disease: Esophageal atresia with or without tracheoesophageal fistula
Esophageal atresia with or without tracheoesophageal fistula 		0.040 Biomarker disease BEFREE All infants with a diagnosis of EA/TEF made within 30days of life who had surgical repair of their defect defined as esophageal reconstruction with or without ligation of TEF within the first six months of life were included. 27993359 2017
CUI: C1861028
Disease: Esophageal atresia with or without tracheoesophageal fistula
Esophageal atresia with or without tracheoesophageal fistula 		0.040 GeneticVariation disease BEFREE Tracheoesophageal fistula, with or without esophageal atresia (TEF/EA) appears to be a defect of blastogenesis, as is the oculoauriculovertebral (Goldenhar) spectrum (OAVS), with which it has occasionally been associated. 7586653 1995
CUI: C1861028
Disease: Esophageal atresia with or without tracheoesophageal fistula
Esophageal atresia with or without tracheoesophageal fistula 		0.040 Biomarker disease BEFREE Esophageal atresia with or without tracheoesophageal fistula (EA +/- TEF) usually occurs sporadically either as an isolated malformation or in conjunction with other congenital anomalies. 6714984 1984