Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.360 GeneticVariation disease UNIPROT
CUI: C0008031
Disease: Chest Pain
Chest Pain
0.100 Biomarker phenotype HPO
CUI: C0010200
Disease: Coughing
Coughing
0.100 Biomarker phenotype HPO
CUI: C0027498
Disease: Nausea and vomiting
Nausea and vomiting
0.100 Biomarker phenotype HPO
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 Biomarker disease HPO
CUI: C0497156
Disease: Lymphadenopathy
Lymphadenopathy
0.100 Biomarker phenotype HPO
CUI: C2674608
Disease: Feeding difficulties in infancy
Feeding difficulties in infancy
0.100 Biomarker phenotype HPO
CUI: C4021776
Disease: Abnormality of the voice
Abnormality of the voice
0.100 Biomarker disease HPO
CUI: C4025741
Disease: Clinodactyly of the 5th toe
Clinodactyly of the 5th toe
0.100 Biomarker disease HPO
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.020 Biomarker group BEFREE DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1. 11118037 2000
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE DLC-1 (deleted in liver cancer 1) is a candidate tumor suppressor gene for hepatocellular carcinoma and other cancers. 12034501 2002
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker disease BEFREE DLC-1 (deleted in liver cancer 1) is a candidate tumor suppressor gene for hepatocellular carcinoma and other cancers. 12034501 2002
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker disease BEFREE DLC-1 was found to be deleted or downregulated in a significant number of HCCs. 12545165 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.020 AlteredExpression group BEFREE DLC-1 overexpression causes inhibition of in vitro growth of liver tumor cells and complete suppression of in vivo tumorigenicity of breast tumor cells. 12792785 2003
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma
0.070 Biomarker disease BEFREE DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. 12813468 2003
Liver and Intrahepatic Biliary Tract Carcinoma
0.070 Biomarker disease BEFREE DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. 12813468 2003
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 Biomarker disease BEFREE DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. 12813468 2003
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker disease BEFREE DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. 12813468 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas. 14661059 2004
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.010 PosttranslationalModification disease BEFREE DLC-1 methylation was shown in 11 of 14 (78%) patients with multiple myeloma and none of the normal controls. 16489177 2006
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.040 Biomarker group BEFREE DLC-1 protein was not detected in 8 of 27 (30%) prostate carcinomas and 11 of 21 (52%) benign prostatic hyperplasias. 16533763 2006
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 PosttranslationalModification disease LHGDN DLEC1 promoter methylation was examined in 13 high-grade ovarian tumor tissues with DLEC1 downregulation, in which 54% of the tumors showed DLEC1 methylation. 16756719 2006
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE DLC-1 (deleted in liver cancer-1) is a tumor suppressor gene for hepatocellular carcinoma and other cancers. 17292327 2007
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE DLC-1 that encodes a Rho GTPase-activating protein, functions as a tumor suppressor gene and is frequently inactivated or down-regulated in several common cancers. 17418982 2007
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.050 Biomarker phenotype BEFREE DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms. 17932950 2008